889947-74-4 Usage
Uses
Used in Pharmaceutical Research:
1-(4-Amino-phenyl)-piperidine-3-carboxylic acid ethyl ester is used as a key intermediate in the synthesis of pharmaceutical compounds for various therapeutic applications. Its structural features allow for the development of new drugs with potential medicinal properties.
Used in Chemical Research:
In the realm of chemical research, 1-(4-Amino-phenyl)-piperidine-3-carboxylic acid ethyl ester serves as a versatile building block for creating novel chemical entities. Its reactivity and functional groups enable the exploration of new chemical reactions and the synthesis of complex molecules.
Used in Drug Development:
1-(4-Amino-phenyl)-piperidine-3-carboxylic acid ethyl ester is utilized in drug development as a precursor to potential therapeutic agents. Its unique structure and functional groups can be modified to create new molecules with specific biological activities, contributing to the discovery of innovative treatments for various diseases.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 1-(4-Amino-phenyl)-piperidine-3-carboxylic acid ethyl ester is employed as a valuable chemical entity for the design and optimization of drug candidates. Its properties and potential applications make it an essential component in the development of new pharmaceuticals with improved efficacy and safety profiles.
Check Digit Verification of cas no
The CAS Registry Mumber 889947-74-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,9,9,4 and 7 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 889947-74:
(8*8)+(7*8)+(6*9)+(5*9)+(4*4)+(3*7)+(2*7)+(1*4)=274
274 % 10 = 4
So 889947-74-4 is a valid CAS Registry Number.
889947-74-4Relevant academic research and scientific papers
SYK INHIBITOR AND USE METHOD THEREFOR
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, (2020/05/07)
Provided are a Syk inhibitor and a use method therefor, and in particular, disclosed are quinolinone represented by formula (I) or quinazoline derivatives or pharmaceutically acceptable salts thereof, a preparation method, a pharmaceutical composition, and uses in preparing a medicament for treatment of Syk receptor related diseases.
Transformation of a selective factor Xa inhibitor rivaroxaban into a dual factor Xa/thrombin inhibitor by modification of the morpholin-3-one moiety
Trstenjak, Uros,Ilas, Janez,Kikelj, Danijel
, p. 197 - 202 (2014/03/21)
Replacement of the P4 morpholin-3-one moiety in a selective factor Xa inhibitor rivaroxaban by 2-ethoxycarbonylpiperidine resulted in a dual factor Xa/thrombin inhibitor 24, possessing a Ki of 62 ± 18 nM for factor Xa and a Ki/
Low molecular weight dual inhibitors of factor Xa and fibrinogen binding to GPIIb/IIIa with highly overlapped pharmacophores
Trstenjak, Uro?,Ila?, Janez,Kikelj, Danijel
, p. 302 - 313 (2013/07/27)
Dual antithrombotic agents acting as anticoagulants and aggregation inhibitors could have substantial advantages over currently prescribed combinations of antithrombotic drugs. Herein, we report compounds with moderate inhibitory activity for factor Xa an
