890090-41-2 Usage
Uses
Used in Bioconjugation:
6-carboxyfluorescein N-hydroxysuccinimide ester is used as a bioconjugation agent for attaching fluorescent dyes to biomolecules such as proteins, peptides, and nucleic acids. This allows for the tracking and visualization of these biomolecules in various biological assays and imaging techniques.
Used in Drug Delivery Systems:
In the pharmaceutical industry, 6-carboxyfluorescein N-hydroxysuccinimide ester is used as a drug delivery agent to improve the targeting and release of therapeutic agents. By attaching the fluorophore to drug molecules or carriers, researchers can monitor the distribution, uptake, and efficacy of the drug in the body.
Used in Biosensors:
6-carboxyfluorescein N-hydroxysuccinimide ester is used as a component in the development of biosensors for detecting specific biomolecules or environmental factors. The fluorescent properties of the dye allow for sensitive and selective detection of target analytes, making it useful in medical diagnostics, environmental monitoring, and other applications.
Used in Cell Biology Research:
In cell biology research, 6-carboxyfluorescein N-hydroxysuccinimide ester is used as a fluorescent probe to study cellular processes such as protein-protein interactions, enzyme activity, and cellular localization. The dye can be attached to specific proteins or other biomolecules to visualize their behavior within living cells.
Used in Immunoassays:
6-carboxyfluorescein N-hydroxysuccinimide ester is used as a labeling agent in immunoassays, such as enzyme-linked immunosorbent assays (ELISA) and fluorescence-based immunoassays. The fluorescent dye allows for sensitive and specific detection of antigen-antibody interactions, making it a valuable tool in diagnostic and research applications.
Check Digit Verification of cas no
The CAS Registry Mumber 890090-41-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,9,0,0,9 and 0 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 890090-41:
(8*8)+(7*9)+(6*0)+(5*0)+(4*9)+(3*0)+(2*4)+(1*1)=172
172 % 10 = 2
So 890090-41-2 is a valid CAS Registry Number.
890090-41-2Relevant academic research and scientific papers
Artificial Ligands of Streptavidin (ALiS): Discovery, Characterization, and Application for Reversible Control of Intracellular Protein Transport
Terai, Takuya,Kohno, Moe,Boncompain, Gaelle,Sugiyama, Shigeru,Saito, Nae,Fujikake, Ryo,Ueno, Tasuku,Komatsu, Toru,Hanaoka, Kenjiro,Okabe, Takayoshi,Urano, Yasuteru,Perez, Franck,Nagano, Tetsuo
supporting information, p. 10464 - 10467 (2015/09/28)
Artificial ligands of streptavidin (ALiS) with association constants of 106 M-1 were discovered by high-throughput screening of our chemical library, and their binding characteristics, including X-ray crystal structure of the streptavidin complex, were determined. Unlike biotin and its derivatives, ALiS exhibits fast dissociation kinetics and excellent cell permeability. The streptavidin-ALiS system provides a novel, practical compound-dependent methodology for repeated reversible cycling of protein localization between intracellular organella.
Design, synthesis, and characterization of fluorescent cobalamin analogues with high quantum efficiencies
Lee, Manfai,Grissom, Charles B.
supporting information; experimental part, p. 2499 - 2502 (2009/10/24)
Cobalamin tethered to fluorescein or Rhodamine 6G has been synthesized and characterized. The fluorophore is conjugated to the ribose-5-OH of cobalamin through a rigid linker to prevent the fluorophore from folding back through space and interacting with
