6-carboxyfluorescein N-hydroxysuccinimide ester

Base Information

Chemical Name:6-carboxyfluorescein N-hydroxysuccinimide ester
CAS No.:890090-41-2
Molecular Formula:C₂₅H₁₅NO₉
Molecular Weight:473.395
Hs Code.:

Synonyms:

Suppliers and Price of 6-carboxyfluorescein N-hydroxysuccinimide ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

BroadPharm
FAMNHSester,6-isomer 98%
50 MG
$ 265.00

Total 2 raw suppliers

Chemical Property of 6-carboxyfluorescein N-hydroxysuccinimide ester

Chemical Property:

Boiling Point:812.2±75.0 °C(Predicted)
Density:1.68±0.1 g/cm3(Predicted)

Purity/Quality:

95% ^*data from raw suppliers

FAMNHSester,6-isomer 98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Description FAM NHS ester, 6-isomer is a hydrophilic fluorophore. The NHS ester can react specifically and efficiently with primary amines such as the side chain of lysine residue or aminosilane-coated surfaces at neutral or slight basic conditions to form a covalent bond.

Technology Process of 6-carboxyfluorescein N-hydroxysuccinimide ester

There total 2 articles about 6-carboxyfluorescein N-hydroxysuccinimide ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 6066-82-6
1-hydroxy-pyrrolidine-2,5-dione

: 108-46-3
recorcinol

: 552-30-7,145253-53-8
trimellitic Anhydride

: 304449-84-1
5-carboxyfluorescein N-hydroxysuccinimide ester

: 890090-41-2
6-carboxyfluorescein N-hydroxysuccinimide ester

Guidance literature:: recorcinol; trimellitic Anhydride; With methanesulfonic acid; at 120 ℃; for 2h;

1-hydroxy-pyrrolidine-2,5-dione; With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; for 12h; Inert atmosphere;
DOI:10.1021/ol900401z

Reference yield:

: 6066-82-6
1-hydroxy-pyrrolidine-2,5-dione

: 76608-15-6
6-carboxyfluorescein

: 890090-41-2
6-carboxyfluorescein N-hydroxysuccinimide ester

Guidance literature:: With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 20 ℃; for 4h; Inert atmosphere;
DOI:10.1021/jacs.5b05672