890315-79-4

Basic information

• Product Name: Benzoic acid, 2-nitro-4-[(1E)-2-phenylethenyl]-, 1,1-dimethylethyl ester
• CAS NO: 890315-79-4
• Molecular Formula: C19H19NO4
• Molecular Weight: 325.364
• Mol File: 890315-79-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 2-nitro-4-[(1E)-2-phenylethenyl]-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2-nitro-4-[(1E)-2-phenylethenyl]-, 1,1-dimethylethyl ester(890315-79-4)
• EPA Substance Registry System: Benzoic acid, 2-nitro-4-[(1E)-2-phenylethenyl]-, 1,1-dimethylethyl ester(890315-79-4)

Safety Data

• Hazardous Substances Data: 890315-79-4(Hazardous Substances Data)

Upstream product

• 99277-71-1 4-bromo-2-nitrobenzoic acid 
• 100-42-5 styrene 
• 890315-72-7 tert-butyl 4-bromo-2-nitrobenzoate 

Relevant articles and documents

NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF

The anthranilic acid derivative or the salt thereof represented by the general formula wherein R1 and R2 are hydrogen atom, or the like; R3 is a phenyl, cycloalkyl or bicyclic heterocyclic group which may be substituted, or the like; R4 is a phenyl, cycloalkyl or pyridyl group which may be substituted, or the like; X1 is an alkylene or alkenylene group which may be substituted or a bond; X2 is the general formula -X3-X4- or -X4-X3-, wherein X3 is a sulfur atom, an imino group or a bond, or the like; X4 means an alkylene or alkenylene group which may be substituted or a bond; is useful for a remedy such as rheumatoid arthritis, osteoarthritis and carcinoma, because it shows MMP-13 production inhibitory effect.

NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF

An anthranilic acid derivative represented by the general formula (X) [wherein R1 represents hydrogen or a carboxy-protecting group; R2 represents optionally substituted phenyl, a heterocyclic group, etc.; R3 represents optionally substituted phenyl, a monocyclic heterocyclic group, etc.; X1 represents carbonyl, etc.; X2 represents optionally substituted alkylene, a bond, etc.; X3 represents oxygen, a bond, etc.; and X4 represents a group represented by the general formula -X5-X6- or -X6-X5- (wherein X5 means oxygen, a bond, etc.; and X6 means optionally substituted alkylene, a bond, etc.)] or a salt of the derivative. The derivative or salt has an MMP-13 production inhibitory activity and is hence useful as a therapeutic agent for articular rheumatisum, osteoarthritis, cancer, etc.