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Upstream product

• 5446-02-6 4-methoxymethylsalicylate 
• 138175-63-0 (Z)-3-Bromo-2-ethylsulfanyl-3-(4-methoxy-phenyl)-acrylonitrile 
• 123-11-5 4-methoxy-benzaldehyde 

Relevant academic research and scientific papers

Synthesis of 3-cyanoflavones and their biological evaluation

The synthesis, using β-bromo-α-ethylthiocinnamonitrile (1) and methyl salicylate (2), of two new series of methyl 2-(2′-cyano-2′-ethylthio-1′-phenylvinyloxy)benzoates (3), precursors of 3-cyanoflavones (4) is reported. Compounds (3) and (4) were checked a

A convenient access to 3-cyanoflavones

Reaction of β-bromo α-alkylthiocinnamonitriles with various substituted methyl salicylates followed by treatment with AlCl 3/PhNO2 provides 3-cyanoflavones.