890409-85-5

Usage

Uses

Used in Polymer Chemistry:
4-(2-pyridinedisulfide)-4-methylvaleric acid succinimide ester is used as a cross-linking agent for enhancing the properties of polymers, such as their stability, strength, and flexibility.
Used in Organic Synthesis:
4-(2-pyridinedisulfide)-4-methylvaleric acid succinimide ester is used as an intermediate in the synthesis of various organic compounds, contributing to the development of new molecules with specific properties.
Used in Materials Science:
4-(2-pyridinedisulfide)-4-methylvaleric acid succinimide ester is used in the development of new materials with unique characteristics, such as improved mechanical properties or specific interactions with other molecules.
Used in Biological Research:
Due to the presence of the pyridinedisulfide group, 4-(2-pyridinedisulfide)-4-methylvaleric acid succinimide ester may have potential biological activity. It is used in research to explore its interactions with biological systems and its potential applications in medicine or other biological fields.

Upstream product

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Relevant academic research and scientific papers

CONJUGATES OF A CELL-BINDING MOLECULE WITH CAMPTOTHECIN ANALOGS

Provided are conjugates of camptothecin analogs with a cell-binding molecule of formula (I), wherein R1, R2, R3, R4, R5, X, L, n, m, T and ----- are defined herein. It also provides methods of making the conjugates of camptothecin analogs to a cell-binding agent, as well as methods of using the conjugates in targeted treatment of cancer, infection, and immunological disorders.

Conjugate of cytotoxin molecule and cell binding receptor molecule

A conjugate of a strong cytotoxin molecule and a cell binding receptor molecule has a structure shown in a molecular formula (I), wherein T, L, m, n, -----, R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12 and R13 are defined in the text. The conjugate is used for treating cancer, immunological diseases and infectious diseases.

CONJUGATE OF CELL-BINDING RECEPTOR WITH CYTOTOXIC AGENT

PROBLEM TO BE SOLVED: To provide a conjugate of a potent cytotoxic agent with a cell-surface receptor binding molecule for targeted treatment. SOLUTION: According to the present invention, there is provided a conjugate having a structure of formula (I) and a pharmaceutical acceptable salt and a solvate thereof. The conjugate is used for treating cancer, autoimmune disease, and infectious disease. (T is a targeting or binding ligand; L is a releasable linker; a broken line is a linkage bond that L connects to a molecule inside the bracket independently; n is an integer of 1 to 20; m is an integer of 1 to 10; and a structure in parentheses is a potent antimitotic agent/drug.) SELECTED DRAWING: None COPYRIGHT: (C)2017,JPOandINPIT

CONJUGATES OF CELL BINDING MOLECULES WITH CYTOTOXIC AGENTS

A conjugate of a potent cytotoxic agent with a cell-surface receptor binding molecule having a formula (I), wherein T, L, m, n, Y, R1, R2, R3, R4, R5, R6, R7, R8, Rsu

Conjugates of Cell Binding Molecules with Cytotoxic Agents

A conjugate of a potent cytotoxic agent with a cell-surface receptor binding molecule having a Formula (I), wherein T, L, m, n, R1, R2, R3, R4, R5, R6, R7, R8, R9