890661-83-3Relevant academic research and scientific papers
INHIBITION OF MONOCYTE SURVIVAL, DIFFERENTIATION, OR PROLIFERATION
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Page/Page column 9-10, (2008/06/13)
Methods comprising administering to the subject apigenin, an apigenin derivative, apigeni and at least one apigenin derivative, or a combination of apigenin derivatives are provided fo treating inflammation in a subject in need of the same.
Synthesis and anti-tubulin evaluation of chromone-based analogues of combretastatins
Quintin, Jér?me,Roullier, Catherine,Thoret, Sylviane,Lewin, Guy
, p. 4038 - 4051 (2007/10/03)
Twenty new hybrid compounds with both combretastatin and flavone moieties were synthesized. These derivatives are classified according to the position of the trimethoxyphenyl ring at C-2 or C-3 of the chromone and presence or absence of a carbonyl as a linker between C-3 and the aryl ring. Most of these compounds were prepared from hesperidin or naringin, two natural and abundant Citrus flavonoids. Seven of these combretastatin analogues revealed anti-tubulin activity but in a medium range.
