890936-73-9Relevant academic research and scientific papers
Synthesis and asymmetric hydrogenation of (3E)-1-benzyl-3-[(2-oxopyridin- 1(2H)-yl)methylidene]piperidine-2,6-dione
Bisset, Alexander A.,Shiibashi, Akira,Desmond, Jasmine L.,Dishington, Allan,Jones, Teyrnon,Clarkson, Guy J.,Ikariya, Takao,Wills, Martin
, p. 11978 - 11980 (2013/01/16)
The synthesis of (3E)-1-benzyl-3-[(2-oxopyridin-1(2H)-yl)methylidene] piperidine-2,6-dione 4 from N-benzylglutarimide was achieved in three steps. The asymmetric hydrogenation of 4 gave either the product of partial reduction (10) or full reduction (13), depending on the catalyst which was employed, in high ee in each case. Attempts at asymmetric transfer hydrogenation (ATH) of 4 resulted in formation of a racemic product. The Royal Society of Chemistry.
A flexible strategy for the synthesis of tri- and tetracyclic lupin alkaloids: Synthesis of (+)-cytisine, (±)-anagyrine, and (±)-thermopsine
Gray, Diane,Gallagher, Timothy
, p. 2419 - 2423 (2007/10/03)
(Chemical Equation Presented) Looping the lupin: A general synthetic strategy for the construction of the lupin alkaloids has been defined and involves sequential formation of the N1-C10 and C6-C7 bonds, which are common to compounds of this class of natu
