891-70-3

Basic information

• Product Name: Benzene, 1-(2-phenylethenyl)-3-(trifluoromethyl)-, (E)-
• CAS NO: 891-70-3
• Molecular Formula: C15H11F3
• Molecular Weight: 248.248
• Mol File: 891-70-3.mol
• Article Data: 30

Chemical Properties

• CAS DataBase Reference: Benzene, 1-(2-phenylethenyl)-3-(trifluoromethyl)-, (E)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-(2-phenylethenyl)-3-(trifluoromethyl)-, (E)-(891-70-3)
• EPA Substance Registry System: Benzene, 1-(2-phenylethenyl)-3-(trifluoromethyl)-, (E)-(891-70-3)

Safety Data

• Hazardous Substances Data: 891-70-3(Hazardous Substances Data)

Upstream product

• 401-78-5 3-bromo-1-trifluoromethylbenzene 
• 1449-46-3 benzyltriphenylphosphonium bromide 
• 68-12-2 N,N-dimethyl-formamide 
• 454-89-7 3-Trifluoromethylbenzaldehyde 
• 1080-32-6 O,O-diethyl benzylphosphonate 
• 349-75-7 3-(trifluoromethyl)benzyl alcohol 
• 16721-45-2 triphenyl(phenylmethylene)phosphorane 
• 401-81-0 m-trifluoromethylphenyl iodide 
• 72761-85-4 trans,trans-1,7-diphenyl-3,3,5,5-tetramethyl-3,5-disila-4-oxahepta-1,6-diene 
• 1100-88-5 benzyltriphenylphosphonium chloride 
• 100-42-5 styrene 
• 98-08-8 α,α,α-trifluorotoluene 
• 98-46-4 3-trifluoromethylnitrobenzene 
• 140-10-3 (E)-3-phenylacrylic acid 

Relevant articles and documents

Non-Chelate-Assisted Palladium-Catalyzed Aerobic Oxidative Heck Reaction of Fluorobenzenes and Other Arenes: When Does the C?H Activation Need Help?

The pyridone fragment in the ligand [2, 2’-bipyridin]-6(1H)-one (bipy-6-OH) enables the oxidative Heck reaction of simple arenes with oxygen as the sole oxidant and no redox mediator. Arenes with either electron-donating or electron-withdrawing groups can be functionalized in this way. Experimental data on the reaction with toluene as the model arene shows that the C?H activation step is turnover limiting and that the ligand structure is crucial to facilitate the reaction, which supports the involvement of the pyridone fragment in the C?H activation step. In the case of fluoroarenes, the alkenylation of mono and 1,2-difluoro benzenes requires the presence of bipy-6-OH. In contrast, this ligand is detrimental for the alkenylation of 1,3-difluoro, tri, tetra and pentafluoro benzenes which can be carried out using just [Pd(OAc)2]. This correlates with the acidity of the fluoroarenes, the most acidic undergoing easier C?H activation so other steps of the reaction such as the coordination-insertion of the olefin become kinetically important for polyfluorinated arenes. The use of just a catalytic amount of sodium molybdate as a base proved to be optimal in all these reactions. (Figure presented.).

Build-up of double carbohelicenes using nitroarenes: Dual role of the nitro functionality as an activating and leaving group

The construction of double carbohelicenes is highly fascinating yet challenging work. Disclosed herein is a streamlined and simplified synthetic route to double carbohelicenes starting from nitroarenes through sequential nitro-activated ortho-C-H arylation, denitrative alkenylation and intramolecular cyclodehydrogenation. In this synthetic strategy, the nitro group plays a dual role namely as a leaving group for the denitrative alkenylation and as an activating group for ortho-C-H arylation, which is distinct from those of aryl halides in a conventional coupling reaction. In this work, the palladium-catalyzed Heck-type alkenylation of nitroarenes has been presented, in which the conventionally inert Ar-NO2 bond is cleaved. This work provides a novel synthetic strategy for polycyclic aromatic hydrocarbons (PAHs). This journal is

Decarboxylative Arylation of α,β-Unsaturated Carboxylic Acids Using Aryl Triazenes by Copper/Ionic Liquid Combination in PEG-400

A practical method for the construction of stilbene derivatives has been developed via catalytic cross-coupling of cinnamic acids with aryl triazenes. The methodology offers high stereoselectivity and is endowed with broad substrate scope, high yield, and significant functional group tolerance.