89108-54-3 Usage
Chemical structure
A compound with a naphthyridinone backbone, a butyl group at the 3-position, a 2-hydroxyethoxy group at the 4-position, and a phenyl group at the 1-position.
Molecular weight
Approximately 393.45 g/mol
Appearance
Likely a solid or crystalline substance, though specific appearance is not provided in the material.
Synthetic compound
It is a synthetically created compound, which means it is not found naturally in the environment.
Pharmaceutical applications
The compound has potential pharmaceutical applications, particularly as an anti-inflammatory, antiviral, or anticancer drug.
Medicinal chemistry
Its specific properties and potential biological activities make it an important compound for further study and development in the field of medicinal chemistry.
Biological activities
The compound's potential as an anti-inflammatory, antiviral, and anticancer agent suggests it may have various biological activities that could be beneficial in treating different medical conditions.
Further research
Due to its potential pharmaceutical applications and biological activities, further research is needed to fully understand the compound's properties, mechanisms of action, and potential side effects.
Chemical stability
Information on the compound's stability under various conditions (e.g., temperature, pH, light exposure) is not provided in the material, but this is an important factor to consider for its potential pharmaceutical applications.
Solubility
The solubility of the compound in different solvents (e.g., water, organic solvents) is not mentioned in the material, but this property is crucial for determining its suitability as a drug candidate.
Toxicity
The material does not provide information on the compound's toxicity, which is an essential factor to consider when evaluating its potential as a pharmaceutical agent.
Synthesis methods
The material does not detail the specific synthetic methods used to create the compound, but understanding these methods can help optimize its production and scalability for pharmaceutical applications.
Structural analogs
The compound may have structural analogs with similar or different properties, which could be explored for their potential pharmaceutical applications.
Patent status
The material does not mention any patents related to the compound, but it is essential to consider intellectual property rights when developing new pharmaceutical agents.
Check Digit Verification of cas no
The CAS Registry Mumber 89108-54-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,9,1,0 and 8 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 89108-54:
(7*8)+(6*9)+(5*1)+(4*0)+(3*8)+(2*5)+(1*4)=153
153 % 10 = 3
So 89108-54-3 is a valid CAS Registry Number.
89108-54-3Relevant academic research and scientific papers
Antiallergy Agents. 1. Substituted 1,8-Naphthyridin-2(1H)-ones as Inhibitors of SRS-A Release
Sherlock, Margaret H.,Kaminski, James J.,Tom, Wing C.,Lee, Joe F.,Wong, Shing-Chun,et al.
, p. 2108 - 2121 (2007/10/02)
A novel class of antiallergy agents, the substituted 1,8-naphthyridin-2(1H)-ones, is described.The present compounds are orally active, potent inhibitors of allergic and nonallergic bronchospasm in animal models.Structure-activity studies of the lead compound in this sereis, 1-phenyl-3-n-butyl-4-hydroxynaphthyridin-2(1H)-one (11), identified three compounds of interest, 1-phenyl-3-(2-propenyl)-4-acetoxy-1,8-naphthyridin-2(1H)-one (12), 1-(3'-chlorophenyl)-3-(2-propenyl)-4-acetoxy-1,8-naphthyridin-2(1H)-one (87), and 1-(3'-methoxyphenyl)-3-(2-propenyl)-4-acetoxy-1,8-naphthyridin-2(1H)-one (89).The mechanism of antiallergy activity may involve inhibition of the release of the sulfidopeptide leukotrienes. 1-Phenyl-3-(2-propenyl)-4-acetoxy-1,8-naphthyridin-2(1H)-one, Sch 33303 (12), was selected for preclinical development as an antiallergy agent.
1-Phenyl-1,8-naphthridin-2(1H)-ones
-
, (2008/06/13)
Certain substituted 1,8-naphthyridines and 1,5,8-azanaphthyridines are useful for treating allergic reactions in mammals. Certain of the compounds may also be utilized to treat chronic obstructive lung diseases in mammals. Methods for preparing the co
Composition containing 1-phenyl-1,8-naphthridin-2(1H)-ones and a non-steroidal anti-inflammatory drug
-
, (2008/06/13)
Certain substitute 1,8-naphthyridines and 1,5,8-azanaphthyridines are useful in treating and preventing ulcers in mammals. Methods for preparing the compounds and methods for their use are also described.
