891201-29-9Relevant academic research and scientific papers
Structural optimization of thiol-based inhibitors of glutamate carboxypeptidase II by modification of the P1′ side chain
Majer, Pavel,Hin, Bunda,Stoermer, Doris,Adams, Jessica,Xu, Weizheng,Duvall, Bridget R.,Delahanty, Greg,Liu, Qun,Stathis, Marigo J.,Wozniak, Krystyna M.,Slusher, Barbara S.,Tsukamoto, Takashi
, p. 2876 - 2885 (2007/10/03)
A series of thiol-based inhibitors containing a benzyl moiety at the P1′ position have been synthesized and tested for their abilities to inhibit glutamate carboxypeptidase II (GCP II). 3-(2-Carboxy-5-mercaptopentyl)- benzoic acid 6c was found to be the m
