89130-31-4Relevant academic research and scientific papers
Visible-light-mediated alkylation of 4-alkyl-1,4-dihydropyridines with alkenyl sulfones
Dong, Jianyang,Liu, Yuxiu,Wang, Qingmin,Yue, Fuyang
, p. 8924 - 8928 (2021/11/04)
Herein we report a mild, general protocol for visible-light-mediated alkylation of 4-alkyl-1,4-dihydropyridines with alkenyl sulfones. The protocol permits efficient functionalization of sulfones with a broad range of cyclic and acyclic secondary and tert
OLEFIN SYNTHESIS USING LITHIUM DERIVATIVES OF N,N,N',N'-TETRAMETHYLDIAMIDES OF ARYLMETHANEPHOSPHONIC ACIDS
Petrova, Jordanka,Kirilov, Marko,Momchilova, Snejana
, p. 29 - 36 (2007/10/02)
The reaction of lithium derivatives of N,N,N',N'-tetramethyldiamides of arylmethanephophonic acids (1-Li) with aldehydes 2 is studied.It is found that under certain reaction conditions (THF, 5 hrs at -70 deg C and then allowing to warm to room temperature) the aldol stage of the reaction is highly stereoselective, only erythro adducts (2-hydroxyphosphonamides) 3, 4 being formed in 47-75percent yields.By heating of 3 and 4 in neutral medium the corresponding (Z)-olefins 5, 6 are obtained (yields 64-74percent).It is established that an acid catalyzed olefination of 2-hydroxyphosphonamides is also possible, but the reaction is not stereospecific.
