1539-32-8

Basic information

• Product Name: 2,6-Dimethyl-4-isopropyl-1,4-dihydro-3,5-pyridinedicarboxylic acid diethyl ester
• Synonyms: 1,4-Dihydro-2,6-dimethyl-4-(1-methylethyl)-3,5-pyridinedicarboxylic acid diethyl ester;1,4-Dihydro-2,6-dimethyl-4-isopropyl-3,5-pyridinedicarboxylic acid diethyl ester;2,6-Dimethyl-4-isopropyl-1,4-dihydro-3,5-pyridinedicarboxylic acid diethyl ester;2,6-Dimethyl-4-isopropyl-1,4-dihydropyridine-3,5-dicarboxylic acid diethyl ester;diethyl 4-isopropyl-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
• CAS NO: 1539-32-8
• Molecular Formula: C₁₆H₂₅NO₄
• Molecular Weight: 295.37
• Mol File: 1539-32-8.mol
• Article Data: 27

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,6-Dimethyl-4-isopropyl-1,4-dihydro-3,5-pyridinedicarboxylic acid diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-Dimethyl-4-isopropyl-1,4-dihydro-3,5-pyridinedicarboxylic acid diethyl ester(1539-32-8)
• EPA Substance Registry System: 2,6-Dimethyl-4-isopropyl-1,4-dihydro-3,5-pyridinedicarboxylic acid diethyl ester(1539-32-8)

Safety Data

• Hazardous Substances Data: 1539-32-8(Hazardous Substances Data)

Usage

Type of compound

Fungicide

Chemical class

Pyridinecarboxylic acids

Mode of action

Inhibition of ergosterol biosynthesis in fungal cell membranes

Uses

Control of plant diseases on fruit and vegetable crops

Toxicity

Low acute toxicity for humans and the environment

Risk classification

Low-risk chemical

Safety precautions

Handle with caution and follow recommended guidelines to minimize health and environmental risks.

Upstream product

• 141-97-9 ethyl acetoacetate 
• 78-84-2 isobutyraldehyde 
• 41867-20-3 ethyl (E)-3-aminobut-2-enoate 
• 133753-76-1 1-(1-Chloro-2-methyl-propyl)-pyridinium; chloride 
• 626-34-6 ethyl 3-aminobut-2-enoate 
• 590-86-3 isovaleraldehyde 
• 57-13-6 urea 
• 626-34-6 ethyl aminocrotonate 
• 506-87-6 ammonium carbonate 

Downstream Products

• 1149-24-2 2,6-dimethyl-pyridine-3,5-dicarboxylic acid diethyl ester 
• 67-63-0 isopropyl alcohol 
• 67-64-1 acetone 
• 1609469-10-4 C₁₃H₁₇NO₄*HNO₂ 
• 103786-20-5 (E)-1-methoxy-4-(3-methyl-but-1-en-1-yl)benzene 
• 13816-33-6 p-Cyanocumen 
• 40463-09-0 4-methyl-1-phenylpentan-3-one 
• 91555-51-0 2-hydroxy-(4'-methoxyphenyl)-3-methylbutanoic acid 
• 2050-07-9 4-methyl-1-phenylpentan-1-one 
• 768-03-6 Phenyl vinyl ketone 
• 21847-98-3 4-methyl-1-(4'-methylphenyl)pentan-1-one 
• 21550-01-6 1-(4'-methoxyphenyl)-4-methylpentan-1-one 
• 21847-96-1 1-(2',4'-dimethylphenyl)-4-metylpentan-1-one 
• 85267-90-9 (+/-)-4-methyl-1,3-diphenylpentan-1-one 

Relevant articles and documents

CeCl3·7H2O-Catalyzed One-Pot Synthesis of Hantzsch 1,4-Dihydropyridines at Room Temperature

An efficient synthesis of a series of 1,4-dihydropyridines was accomplished at room temperature by the reaction of aldehydes with ammonium acetate and ethyl acetoacetate catalyzed by CeCl3·7H2O.

Visible-light-mediated alkylation of 4-alkyl-1,4-dihydropyridines with alkenyl sulfones

Herein we report a mild, general protocol for visible-light-mediated alkylation of 4-alkyl-1,4-dihydropyridines with alkenyl sulfones. The protocol permits efficient functionalization of sulfones with a broad range of cyclic and acyclic secondary and tert

Visible-light-mediated minisci C-H alkylation of heteroarenes with 4-alkyl-1,4-dihydropyridines using O2as an oxidant

Herein, we report a protocol for direct visible-light-mediated Minisci C-H alkylation reactions of N-heteroarenes with 4-alkyl-1,4-dihydropyridines at room temperature with molecular oxygen as an oxidant. The protocol permits efficient functionalization of various N-heteroarenes with a broad range of cyclic and acyclic primary, secondary, and tertiary alkyl groups and is scalable to the gram level. This mild protocol uses an inexpensive, green oxidant and is suitable for late-stage C-H alkylation of complex nitrogen-containing molecules. We demonstrated its utility by preparing or functionalizing several pharmaceuticals and natural products.