89185-83-1

Basic information

• Product Name: 2,4-Pentanedione, 3-(4-nitrophenyl)-
• CAS NO: 89185-83-1
• Molecular Formula: C11H11NO4
• Molecular Weight: 221.213
• Mol File: 89185-83-1.mol

Chemical Properties

• CAS DataBase Reference: 2,4-Pentanedione, 3-(4-nitrophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-Pentanedione, 3-(4-nitrophenyl)-(89185-83-1)
• EPA Substance Registry System: 2,4-Pentanedione, 3-(4-nitrophenyl)-(89185-83-1)

Safety Data

• Hazardous Substances Data: 89185-83-1(Hazardous Substances Data)

Usage

Physical form

Yellow crystalline powder

Solubility

Slightly soluble in water

Usage

Reagent in organic synthesis, production of pharmaceuticals and fine chemicals, manufacturing of dyes and pigments, potential applications in medicine

Hazards

Can be hazardous if not handled properly, precautions should be taken.

Upstream product

• 5332-96-7 1-(4-nitrophenyl)propan-2-one 
• 108-24-7 acetic anhydride 
• 586-78-7 para-nitrophenyl bromide 
• 123-54-6 acetylacetone 
• 636-98-6 p-nitrobenzene iodide 
• 456-27-9 4-nitrobenzenediazonium tetrafluoroborate 
• 132619-03-5 (E)-(4-Nitrophenyl)azo phenyl sulfide 

Downstream Products

• 1377326-33-4 Ti₁₀O₂₄(isopropoxide)16(3-(4-nitrophenyl)pentane-2,4-dionato)4 
• 6159-25-7 1-<(4-nitro)-phenyl>-1,2-propandione 
• 1278456-10-2 C₁₄H₁₅NO₄ 
• 42418-61-1 3,5-dimethyl-4-(4-nitrophenyl)-1H-pyrazole 
• 2155-99-9 4-(3,5-dimethylisoxazol-4-yl)aniline 
• 1160169-37-8 1-(3-methyl-2-(4-nitrophenyl)-2H-azirin-2-yl)ethanone 
• 1331858-09-3 C₂₁H₂₁NO₃ 
• 1278456-17-9 C₁₆H₁₉NO₃ 
• 1331858-10-6 C₁₈H₂₃NO₃ 
• 1278456-12-4 C₁₅H₁₇NO₃ 
• 1160169-23-2 (Z)-4-amino-3-(4-nitrophenyl)pent-3-en-2-one 
• 2155-98-8 3,5-dimethyl-4-(4-nitrophenyl)isoxazole 

Relevant articles and documents

SMALL MOLECULE MODULATORS OF IL-17

The present invention relates to a compound according to formula (I), (I) and pharmaceutically acceptable salts, hydrates, or solvates thereof. The invention further relates to said compounds for use in therapy, to pharmaceutical compositions comprising said compounds, to methods of treating diseases, e.g. dermal diseases, with said compounds, and to the use of said compounds in the manufacture of medicaments.

AMINO-ACID ANILIDES AS SMALL MOLECULE MODULATORS OF IL-17

The present invention relates to a compound according to formula I (I) and pharmaceutically acceptable salts, hydrates, or solvates thereof. The invention further relates to said compounds for use in therapy, to pharmaceutical compositions comprising said compounds, to methods of treating diseases, e.g. dermal diseases, with said compounds, and to the use of said compounds in the manufacture of medicaments.

Iron-catalyzed aerobic oxidative cleavage of the C-C σ-bond using air as the oxidant: Chemoselective synthesis of carbon chain-shortened aldehydes, ketones and 1,2-dicarbonyl compounds

A simple iron-catalyzed aerobic oxidative C-C σ-bond cleavage of ketones has been developed. Readily available and environmentally benign air is used as the oxidant. This reaction avoids the use of noble metal catalysts or specialized oxidants, chemoselectively yielding carbon chain-shortened aldehydes, ketones and 1,2-dicarbonyl compounds without overoxidation.

Interfacial electron transfer into functionalized crystalline polyoxotitanate nanoclusters

Interfacial electron transfer (IET) between a chromophore and a semiconductor nanoparticle is one of the key processes in a dye-sensitized solar cell. Theoretical simulations of the electron transfer in polyoxotitanate nanoclusters Ti17O24

Copper(II) and 1,1′-trimethylene-2,2′-biimidazole-promoted arylation of acetylacetone with aryl iodides

A new and efficient way was developed to carry out the reaction of acetylacetone with aryl iodides under the assistance of Cu(II) and 1,1′-trimethylene-2,2′-biimidazole at 100°C. 3-Aryl-2,4-pentanediones were obtained in excellent yields. Copyright

Deacylative allylation of nitroalkanes: Unsymmetric bisallylation by a three-component coupling

Use it and lose it! Allylic alcohols were used directly for the synthesis of diallylated nitroalkanes in a three-component coupling based on the strategy of deacylative allylation for the in situ generation of a nucleophile and an allyl electrophile (see

Deacylative allylation: Allylic alkylation via retro-Claisen activation

A new method for allylic alkylation of a variety of relatively nonstabilized carbon nucleophiles is described herein. In this process of "deacylative allylation", the coupling partners, an allylic alcohol and a ketone pronucleophile, undergo in situ retro-Claisen activation to generate an allylic acetate and a carbanion. In the presence of palladium, these reactive intermediates undergo catalytic coupling to form a new C-C bond. In comparison to unimolecular decarboxylative allylation, a commonly utilized method for allylation of carbon anions, deacylative allylation is an intermolecular process. Moreover, deacylative allylation allows the direct coupling of readily available allylic alcohols. Lastly, the full utility of deacylative allylation is demonstrated by the rapid construction of a variety 1,6-heptadienes via 3-component couplings.

C-arylation reactions catalyzed by CuO-nanoparticles under ligand free conditions

CuO-nanoparticles were found to be an excellent heterogeneous catalyst for C-arylation of active methylene compounds using various aryl halides. The products were obtained in good to excellent yield. The catalyst can be recovered and reused for four cycles with almost no loss in activity.

ANTIFUNGAL AGENTS

Compounds of formula (I), and pharmaceutically acceptable salts thereof, may be used in therapy, for example as antifungal agents: (I) wherein: Rl, R2, R3, R4, R5, R6, R7, X and X1 are as defined herein. Certain compounds of formula (I) are also provided. Compounds of formula (T), and agriculturally acceptable salts thereof, may also be used as agricultural fungicides.

Arylation of potassium 2,4-pentanedionate via S(RN)1 on diazosulfides

Potassium 2,4-pentanedionate reacts with diazosulfides (E)-1 and (Z)-2 in DMSO to give 3-aryl-2,4-pentanediones 3 via an S(RN)1 process. Advantages and drawbacks of such new access to 3 are reported together with relevant mechanistic implications.