891863-22-2Relevant academic research and scientific papers
Alternative Palladium-Catalyzed Vinylic C?H Difluoroalkylation of Ketene Dithioacetals Using Bromodifluoroacetate Derivatives
Tian, Shuangquan,Song, Xiaoning,Zhu, Dongsheng,Wang, Mang
, p. 1414 - 1419 (2018/04/10)
A palladium-catalyzed cross-coupling of α-oxo ketene dithioacetals and bromodifluoroacetate derivatives has been developed for the synthesis of a class of CF2-containing tetra-substituted olefins, which has potential to extend to drug design an
Catalytic synthesis of α-Oxoketene S,S-acetals in a wet ionic liquid [Bmim]Cl/H2O homogeneous system
Yu, Ping,Zu, Yuangang,Fu, Yujie,Efferth, Thomas
experimental part, p. 4500 - 4510 (2011/08/10)
A clean, practical and environmentally friendly synthesis in a homogeneous system has been developed for α-oxoketene S,S-acetals. A mixture of [Bmim]Cl and water was used as medium. The best economical and practical molar ratio of [Bmim]Cl to substrate was 4 to 1. With various types of 1,3-dicarbonyl compounds as substrate, the corresponding α-oxoketene S,S-acetals have been prepared under mild reaction conditions with yields of 53-74% after purification with silica gel column. [Bmim]Cl/water can be recycled several times.
A facile synthetic route to highly functionalized 2,4-pyrrolidinediones: A new base-catalyzed cyclization
Jin, Yu-Zi,Zhu Yin, Bing,Lee, Youn-Sik
, p. 357 - 368 (2007/10/03)
2,4-Pyrrolidinedione derivatives were synthesized in 67-85% yield in one-pot reaction via base-catalyzed cyclization of α-(arylvinylcarbonyl)-α′-(N-arylaminocarbonyl)ketene dithioacetals formed in situ by the reaction of a-acetyl-α′-(N-arylaminocarbonyl)k
