89201-08-1

Basic information

• Product Name: Propanedioic acid, (2-oxo-2-phenylethylidene)-, diethyl ester
• Synonyms: Propanedioic acid,(2-oxo-2-phenylethylidene)-,diethyl ester
• CAS NO: 89201-08-1
• Molecular Formula: C15H16O5
• Molecular Weight: 276.289
• Mol File: 89201-08-1.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: Propanedioic acid, (2-oxo-2-phenylethylidene)-, diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Propanedioic acid, (2-oxo-2-phenylethylidene)-, diethyl ester(89201-08-1)
• EPA Substance Registry System: Propanedioic acid, (2-oxo-2-phenylethylidene)-, diethyl ester(89201-08-1)

Safety Data

• Hazardous Substances Data: 89201-08-1(Hazardous Substances Data)

Upstream product

• 20913-05-7 (Benzoylmethylene)triphenylphosphorane 
• 609-09-6 Diethyl ketomalonate 
• 71639-13-9 diethyl 2-(3-nitrophenylethyl)malonate 
• 1164124-57-5 (2R,3S)-diethyl 2-nitro-3-phenylcyclopropane-1,1-dicarboxylate 
• 3092-20-4 diethyl 2-phenylcyclopropane-1,1-dicarboxylate 
• 106352-23-2 diethyl 2-phenylcycloprop-2-ene-1,1-dicarboxylate 
• 5256-74-6 1,3-diethyl 2-diazopropanedioate 
• 536-74-3 phenylacetylene 
• 105-53-3 diethyl malonate 
• 98-86-2 acetophenone 

Downstream Products

• 1593957-91-5 ethyl (2-methyl-5-phenyl-1H-imidazol-4-yl)acetate 
• 5021-43-2 2-phenylquinoxaline 
• 71897-07-9 AG₁₂₉₅ 
• 1593958-02-1 diethyl 2-(3-phenyl-2H-benzo[1,4]thiazin-2-yl)malonate 
• 1605320-73-7 tetraethyl 2-benzoylpropane-1,1,3,3-tetracarboxylate 

Relevant articles and documents

Synthesis and biological evaluation of new 1,4-benzothiazine derivatives as potential COX-2 inhibitors

A series of new 2H-benzo[1,4]thiazine derivatives were synthesized from aroylmethylidene malonates and o-aminothiophenols by condensation/cyclization methodology in order to evaluate their COX-2 inhibitory activity. In-silico studies indicated that among

Organocatalytic enantioselective conjugate addition of pyrazolin-5-ones to arylomethylidene malonates

An efficient asymmetric organocatalytic conjugate addition reaction of pyrazolin-5-ones with arylomethylidene malonates has been successfully developed by employing bifunctional Cinchona derived thiourea organocatalysts. The protocol provides straightforward access to pyrazole substituted scaffolds in good yields with high stereocontrol.