892242-64-7

Upstream product

• 82-45-1 1-amino-9,10-anthracenedione 
• 81-49-2 1-amino-2, 4-dibromoanthraquinone 
• 82840-40-2 3,5-dibromo-6-oxo-6H-anthra<1,9-cd>isoxazole 
• 150-13-0 4-amino-benzoic acid 
• 17766-28-8 cyclohexylpiperazine 

Relevant academic research and scientific papers

PROCESS OF PREPARING TYROSINE KINASE INHIBITOR

The invention relates to a process for preparing sodium 4-((3-(4-cyclohexylpiperazin-1-yl)-6-oxo-6H-anthra[1,9-cd]isoxazol-5-yl)amino)benzoate.

CRYSTALLINE FORMS OF TYROSINE KINASE INHIBITORS AND THEIR SALTS

The disclosure relates to various polymorphic forms and amorphous form of sodium 4-((3-(4-cyclohexylpiperazin-1-yl)-6-oxo-6H-anthra[1,9-cd]isoxazol-5-yl)amino)benzoate, including the polymorphic form A, mixtures of the polymorphs, process for the preparation thereof and the use thereof in a pharmaceutical composition containing thereof.

COMPOSITIONS OF COMPOUNDS AND USES THEREOF

The present disclosure relates to novel synthetic substituted heterocyclic compounds and pharmaceutical compositions containing the same. The disclosure further concerns the use of such compounds in the treatment and/or prevention of certain types of cancers, pain, inflammation, restenosis, atherosclerosis, psoriasis, thrombosis, Alzheimer's, a disease, disorder, injury, or malfunction relating to dysmyelination or demyelination.