892390-46-4Relevant academic research and scientific papers
Scalable Approach to Fluorinated Heterocycles with Sulfur Tetrafluoride (SF4)
Trofymchuk, Serhii,Bugera, Maksym,Klipkov, Anton A.,Ahunovych, Volodymyr,Razhyk, Bohdan,Semenov, Sergey,Boretskyi, Andrii,Tarasenko, Karen,Mykhailiuk, Pavel K.
, p. 12181 - 12198 (2021/09/13)
A general approach to fluorinated (hetero)aromatic derivatives is elaborated. The key reaction is a deoxofluorination of substituted acetophenones with sulfur tetrafluoride (SF4). In contrast to previous deoxofluorination methods, this transformation is fast, scalable (up to 70 g), and high-yielding. More than 100 novel or previously hardly accessible fluorinated heterocycles, interesting for medicinal chemistry and agrochemistry, were synthesized.
Silver-catalyzed oxidative activation of benzylic C-H bonds for the synthesis of difluoromethylated arenes
Xu, Peng,Guo, Shuo,Wang, Liyan,Tang, Pingping
supporting information, p. 5955 - 5958 (2014/06/10)
A mild and catalytic method to form difluoromethylated arenes through the activation of benzylic C-H bonds has been developed. Utilizing AgNO3 as the catalyst, various arenes with diverse functional groups undergo activation/fluorination of ben
NOVEL COMPOUNDS
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Page/Page column 46-47, (2008/06/13)
A compound of Formula (I) and pharmaceutically and/or veterinarily acceptable derivatives thereof, wherein: R1 is H, C1-6alkyl, - C(A)D, C3-8cycloalkyl, aryl, het, aryl-C1-4alkyl or het-C1-4/sub
