89250-49-7Relevant academic research and scientific papers
Ionization, tautomerism and molecular conformation in aqueous solution of the histamine H2-receptor antagonist mifentidine
Bazzano,Vavoni,Mondoni,et al.
, p. 27 - 33 (2007/10/02)
Ionization (pK(a)) and tautomeric (K(t)) constants of mifentidine (DA4577) have been determined in aqueous solution. The predominant molecular species at physiological pH (7.4) is the monocationic form (95.3%) at the formamidine moiety, with the imidazole
