893395-89-6Relevant academic research and scientific papers
PROCESS FOR THE PREPARATION OF CHIRAL AMINES
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Page/Page column 9-10, (2008/06/13)
The invention relates to a process for the preparation of a chiral amine, whereby a ketone or aldehyde is contacted with an enantiomerically enriched phenylglycine amide to give an imine, whereby the imine is subsequently contacted with a Reformatsky reagent and the formed compound is subsequently converted into a chiral amine by means of hydrogenolysis, oxidation or a retro Strecker method.
