893422-47-4 Usage
General Description
3-Phenyl-2-[4-[[4-[5-(2-pyridinyl)-1H-1,2,4-triazol-3-yl]-1-piperidinyl]methyl]phenyl]-1,6-Naphthyridin-5(6H)-one is a complex chemical compound with a long and intricate molecular structure. It contains multiple aromatic rings and nitrogen-containing heterocycles, making it potentially valuable for medicinal or pharmaceutical applications. The compound's structural features suggest that it may have potential biological activity, possibly as a receptor ligand or enzyme inhibitor. However, further research and testing would be necessary to determine its precise properties and potential uses.
Check Digit Verification of cas no
The CAS Registry Mumber 893422-47-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,9,3,4,2 and 2 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 893422-47:
(8*8)+(7*9)+(6*3)+(5*4)+(4*2)+(3*2)+(2*4)+(1*7)=194
194 % 10 = 4
So 893422-47-4 is a valid CAS Registry Number.
893422-47-4Relevant articles and documents
Discovery of potent and cell-active allosteric dual Akt 1 and 2 inhibitors
Siu, Tony,Liang, Jun,Arruda, Jeannie,Li, Yiwei,Jones, Raymond E.,Defeo-Jones, Deborah,Barnett, Stanley F.,Robinson, Ronald G.
scheme or table, p. 4186 - 4190 (2009/04/07)
This paper describes the improvement of cell potency in a class of allosteric Akt 1 and 2 inhibitors. Key discoveries include identifying the solvent exposed region of the molecule and appending basic amines to enhance the physiochemical properties of the
INHIBITORS OF AKT ACTIVITY
-
, (2010/11/25)
The instant invention provides for substituted naphthyridine compounds that inhibit Akt activity. In particular, the compounds disclosed selectively inhibit one or two of the Akt isoforms. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting Akt activity by administering the compound to a patient in need of treatment of cancer.