893428-67-6

Basic information

• Product Name: 4(3H)-Quinazolinone, 7-[2-(4-Methyl-1-piperazinyl)ethoxy]-5-[(tetrahydro-2H-pyran-4-yl)oxy]-
• Synonyms: 4(3H)-Quinazolinone, 7-[2-(4-Methyl-1-piperazinyl)ethoxy]-5-[(tetrahydro-2H-pyran-4-yl)oxy]-;7-(2-(4-methylpiperazin-1-yl)ethoxy)-5-(tetrahydro-2H-pyran-4-yloxy)quinazolin-4(3H)-one
• CAS NO: 893428-67-6
• Molecular Formula: C20H28N4O4
• Molecular Weight: 388.46072
• Mol File: 893428-67-6.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4(3H)-Quinazolinone, 7-[2-(4-Methyl-1-piperazinyl)ethoxy]-5-[(tetrahydro-2H-pyran-4-yl)oxy]-(CAS DataBase Reference)
• NIST Chemistry Reference: 4(3H)-Quinazolinone, 7-[2-(4-Methyl-1-piperazinyl)ethoxy]-5-[(tetrahydro-2H-pyran-4-yl)oxy]-(893428-67-6)
• EPA Substance Registry System: 4(3H)-Quinazolinone, 7-[2-(4-Methyl-1-piperazinyl)ethoxy]-5-[(tetrahydro-2H-pyran-4-yl)oxy]-(893428-67-6)

Safety Data

• Hazardous Substances Data: 893428-67-6(Hazardous Substances Data)

Upstream product

• 379228-59-8 7-fluoro-5-((tetrahydro-2H-pyran-4-yl)oxy)quinazoline-4(3H)-one 
• 379228-58-7 5,7-difluoroquinazolin-4(3H)-one 
• 5464-12-0 2-(4-methylpiperazinyl)ethanol 
• 379230-38-3 7-fluoro-N-(5-chloro-1,3-benzodioxol-4-yl)-5-(tetrahydro-2H-pyran-4-yloxy)quinazolin-4-amine 
• 791602-75-0 4-chloro-5,7-difluoroquinazoline 

Relevant articles and documents

QUINAZOLINE DERIVATIVES AS TAM FAMILY KINASE INHIBITORS

Disclosed are compounds, compositions and methods for treating diseases, syndromes, conditions and disorders that are affected by the modulation of the activity of, e.g., the inhibition of, one or more members of the TAM family kinases.

CHEMICAL PROCESS

The present invention relates to chemical processes useful in the manufacture of the compound 4-(6-chloro-2,3-methylenedioxyanilino)-7-[2-(4-methylpiperazin-1-yl)ethoxy]- 5-tetrahydropyran-4-yloxyquinazoline (the active entity within AZD0530), to intermed