89358-47-4Relevant academic research and scientific papers
Potassium carbonate promoted nucleophilic addition of alkenes with phosphites
Huang, Zhenjun,Liu, Wei,Li, Sen,Yang, Yutian,Guo, Shengmei,Cai, Hu
supporting information, p. 1295 - 1297 (2020/08/21)
A facile hydrophosphonylation of alkenes by phosphites promoted by potassium carbonate was developed. The reaction features include easy handling, environmental friendliness, and avoidance of the use of strong bases. A variety of alkenes are tolerated in this reaction, with moderate to excellent yields.
Hydrophosphination of Activated Alkenes by a Cobalt(I) Pincer Complex
Nolla-Saltiel, Roberto,Geer, Ana M.,Taylor, Laurence J.,Churchill, Olivia,Davies, E. Stephen,Lewis, William,Blake, Alexander J.,Kays, Deborah L.
, p. 3148 - 3157 (2020/06/08)
Herein we report the synthesis of three heteroleptic first-row transition metal(II) complexes containing carbazolido NNN pincer ligands and conversion to the corresponding metal(I)-carbonyl complexes via a reductive carbonylation route. These complexes are precatalysts for the hydrophosphination of activated alkenes, affording a cobalt-catalysed hydrophosphination process that solely and selectively yields the β addition (anti-Markovnikov) product. The scope of this transformation has been investigated using a variety of activated alkenes. Isolation and characterisation of substrate-coordinated intermediates reveal available coordination sites, which provide insight into the proposed catalytic cycle. (Figure presented.).
Synthesis of new phosphonoamide and phosphonocaprolactam derivatives via the diethyl chlorophosphate-promoted beckmann rearrangement of γ-phosphonyloximes
Wahbi, Aymen,Touil, Soufiane
, p. 397 - 404 (2017/02/14)
ABSTRACT: Herein, we report an efficient and straightforward synthesis of new phosphonoamide and phosphonocaprolactam derivatives, via the Beckmann rearrangement of γ-phosphonyloximes. The reaction proceeded smoothly in the presence of diethyl chlorophosp
Efficient synthesis of 4-phosphinoyl-4,5,6,7-tetrahydro-2H-indazol-3- ylamines
Jelaiel, Nourchaine,Comoy, Corinne,Fernette, Brigitte,Efrit, Mohamed Lofti,Fort, Yves
experimental part, p. 9440 - 9445 (2011/12/14)
We described in this paper an efficient synthesis of variously substituted 4-phosphinoyl-4,5,6,7-tetrahydro-2H-indazol-3-ylamines involving nucleophilic addition of hydrazine on β-ketothioamides as key-step.
Palladium(II)-catalyzed conjugate phosphination of electron-deficient acceptors
Trepohl, Verena T.,Mori, Susumu,Itami, Kenichiro,Oestreich, Martin
supporting information; experimental part, p. 1091 - 1094 (2009/07/25)
A general protocol for the conjugate transfer of diphenyl-, dicyclohexyl-, and di-tert-butylphosphinyl groups from silylphosphines to cyclic and acyclic electron-deficient acceptors employing a bench-stable palladium(II) catalyst is reported. Several Eand
Conjugate phosphination of cyclic and acyclic acceptors using Rh(I)-phosphine or Rh(I)-carbene complexes. Probing the mechanism with chirality at the silicon atom or the phosphorus atom of the Si-P reagent
Trepohl, Verena T.,Fr?hlich, Roland,Oestreich, Martin
scheme or table, p. 6510 - 6518 (2011/02/26)
The Rh(I)-catalyzed conjugate phosphinyl transfer from an Si-P reagent to an electron-deficient acceptor requires individual protocols for cyclic and acyclic α,β-unsaturated carbonyls and carboxyls. While 1,4-addition to cyclic acceptors is catalyzed by a
Catalytic conjugate additions of nitrogen-, phosphorus-, and carbon-containing nucleophiles by amphoteric vanadyl triflate
Lin, Yow-Dzer,Kao, Jun-Qi,Chen, Chien-Tien
, p. 5195 - 5198 (2008/09/17)
(Chemical Equation Presented) A series of carbamates, amides, N-tosyl amides, (hetero)arenes, and hydrogen phosphines/phosphites has been examined as nucleophiles for (hetero)Michael-type additions to enones and enamides catalyzed by amphoteric vanadyl triflate under mild and neutral conditions. The newly developed C-N, C-P, and C-C bond-formation protocols were carried out smoothly in good to high yields without intervention of any 1,2-additions.
Rhodium(I)-catalysed conjugate phosphination of cyclic α,β- unsaturated ketones with silylphosphines as masked phosphinides
Trepohl, Verena T.,Oestreich, Martin
, p. 3300 - 3302 (2008/02/13)
Nucleophile-activation of the phosphorus(iii)-silicon linkage in silylphosphines generates a nucleophilic phosphorus(iii) equivalent thereby allowing for a rhodium-catalysed conjugate phosphination of β-substituted α,β-unsaturated acceptors. The Royal Soc
Fluoride-mediated phosphination of alkenes and alkynes by silylphosphines
Hayashi, Minoru,Matsuura, Yutaka,Watanabe, Yutaka
, p. 9167 - 9169 (2007/10/03)
Regioselective phosphination of carbon-carbon unsaturated bonds by a fluoride-mediated reaction of silylphosphines is described. Alkenes and alkynes having a directing group, such as an aromatic or a carbonyl group, reacted to form a carbon-phosphorus bon
Synthesis of β-(Diphenylphosphinoyl) Ketones
Bell, Andrew,Davidson, Alan H.,Earnshaw, Chris,Norrish, Howard K.,Torr, Richard S.,et al.
, p. 2879 - 2892 (2007/10/02)
The title compounds may be made by addition of phosphorus nucleophiles (Ph2PO-, Ph2POMgX, Ph2PCl) to enones, by addition of phosphorus-stabilised carbanions to a α-carbonyl cation equivalents (2,3-dichloropropene, epoxides, and α-MeO-ketones) and by oxidation of allyl diphenylphosphine oxides.
