89374-41-4Relevant academic research and scientific papers
4 H - pyrido [3, 2 - e] [1, 3] thiazine - 4 - ketone derivative and its application
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, (2017/11/16)
The invention relates to the technical field of medicines, discloses a novel 4H-pyridino-[3,2-e][1,3]thiazine-4-ketone derivate and an application thereof, and designs and synthesizes a series of novel-structure 4H-pyridino-[3,2-e][1,3]thiazine-4-ketone c
Synthesis, structure-activity relationships, and anticonvulsant activities of 2-amino-4H-pyrido[3,2-e][1,3]thiazin-4-one derivatives as orally active AMPA receptor antagonists
Inami, Hiroshi,Shishikura, Jun-Ichi,Yasunaga, Tomoyuki,Ohno, Kazushige,Yamashita, Hiroshi,Kato, Kota,Sakamoto, Shuichi
, p. 1788 - 1799 (2015/03/30)
As part of a program aimed at discovering orally active 2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid (AMPA) receptor antagonists, we screened our compound library and identified 2-[allyl(4-methylphenyl)amino]-4H-pyrido[3,2-e][1,3]thiazin-4-on
