89395-29-9

Basic information

• Product Name: (3aR,7aS)-hexahydroisobenzofuran-1-one
• Synonyms: (3aR,7aS)-hexahydroisobenzofuran-1-one
• CAS NO: 89395-29-9
• Molecular Weight: 140.182
• Mol File: 89395-29-9.mol
• Article Data: 21

Chemical Properties

• CAS DataBase Reference: (3aR,7aS)-hexahydroisobenzofuran-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (3aR,7aS)-hexahydroisobenzofuran-1-one(89395-29-9)
• EPA Substance Registry System: (3aR,7aS)-hexahydroisobenzofuran-1-one(89395-29-9)

Safety Data

• Hazardous Substances Data: 89395-29-9(Hazardous Substances Data)

Upstream product

• 13149-00-3 1,2-cis-cyclohexanedicarboxylic anhydride 
• 15753-50-1 cis-1,2-cyclohexanedimethanol 
• 54211-18-6 bicyclo[4.2.0]octan-7-one 
• 92670-99-0 cis-2-phenyl-octahydroisoindole-1,3-dione 
• 64090-28-4 2-methylhexahydro-1H-isoindole-1,3(2H)-dione 
• 27655-70-5 cis-bicyclo-[4.2.0]-octan-7-one 
• 77210-71-0 (+)-(1S,6R)-8-cis-oxabicyclo[4.3.0]non-3-en-7-one 
• 102307-20-0 2-ketoadipate monosodium salt 
• 86331-49-9 2-Hydroxymethyl-cyclohexanecarboxylic acid ((R)-2-hydroxy-1-phenyl-ethyl)-amide 
• 66050-00-8 2-benzylhexahydro-1H-isoindole-1,3(2H)-dione 
• 5059-76-7 ((1R,3S)-cyclohexane-1,3-diyl)dimethanol 

Downstream Products

• 65376-04-7 (-)-(1R,2R)-trans-2-(hydroxymethyl)cyclohexanoic acid 
• 610-09-3 (1R,2S)-cyclohexane-1,2-dicarboxylic acid 
• 13185-53-0 (1S,2R)-1-Methyl-cyclohexane-1,2-dicarboxylic acid 
• 116261-07-5 (1S,2R)-2-hydroxymethyl-1-cyclohexanecarboxamide 
• 65376-05-8 (+)-(1R,2R)-trans-1,2-bis(hydroxymethyl)cyclohexane 
• 496811-06-4 (1S,2R)-2-(1,3-Dioxo-1,3-dihydro-isoindol-2-ylmethyl)-cyclohexanecarboxylic acid 

Relevant articles and documents

Simple Preparation of Rhodococcus erythropolis DSM 44534 as Biocatalyst to Oxidize Diols into the Optically Active Lactones

In the current study, we present a green toolbox to produce ecological compounds like lactone moiety. Rhodococcus erythropolis DSM 44534 cells have been used to oxidize both decane-1,4-diol (2a) and decane-1,5-diol (3a) into the corresponding γ- (2b) and δ-decalactones (3b) with yield of 80% and enantiomeric excess (ee)?=?75% and ee?=?90%, respectively. Among oxidation of meso diols, (?)-(1S,5R)-cis-3-oxabicyclo[4.3.0]non-7-en-2-one (5a) with 56% yield and ee?=?76% as well as (?)-(2R,3S)-cis-endo-3-oxabicyclo[2.2.1]dec-7-en-2-one (6a) with 100% yield and ee?=?90% were formed. It is worth mentioning that R. erythropolis DSM 44534 grew in a mineral medium containing ethanol as the sole source of energy and carbon Chirality 28:623–627, 2016.

Aerobic oxidative desymmetrization of meso-diols with bifunctional amidoiridium catalysts bearing chiral N-sulfonyldiamine ligands

Asymmetric aerobic oxidation of a range of meso- and prochiral diols with chiral bifunctional Ir catalysts is described. A high level of chiral discrimination ability of Cpa? -Ir complexes derived from (S,S)-1,2-diphenylethylenediamine was successfully demonstrated by desymmetrization of secondary benzylic diols such as cis-indan-1,3-diol and cis-1,4-diphenylbutane-1,4-diol, providing the corresponding (R)-hydroxyl ketones with excellent chemo- and enantioselectivities. Enantiotopic group discrimination in oxidation of symmetrical primary 1,4- and 1,5-diols gave rise to chiral lactones with moderate ees under similar aerobic conditions.

Catalytic Preparation of Cyclic Carboxylic Esters

Preparation of cyclic esters by hydrogenation of a carbonyl group in at least one anhydride radical —C(O)—O—C(O)— of a cyclic dicarboxylic or polycarboxylic anhydride by means of hydrogen in the presence of a homogeneous noble metal catalyst, characterized in that the hydrogenation is carried out in a homogeneous reaction mixture using an iridium catalyst. The cyclic esters are obtained in good chemical and optical yields when prochiral anhydrides are used together with chiral iridium catalysts.