894401-46-8

Upstream product

• 894400-31-8 N-(4-iodophenyl)-N-methyl-2-pyrimidinylamine 
• 106928-50-1 methyl 2-[(tert-butoxycarbonyl)amino]pent-4-enoate 
• 540-37-4 p-aminoiodobenzene 
• 119479-32-2 2-((tert-butyloxycarbonyl)amino)-4-pentenoic acid 
• 24424-99-5 di-tert-butyl dicarbonate 
• 894400-24-9 N-(4-iodophenyl)pyrimidin-2-amine 

Downstream Products

• 894401-36-6 2-amino-5-[4-(methyl-pyrimidin-2-ylamino)phenyl]pent-4-enoic acid methyl ester 

Relevant academic research and scientific papers

THERAPEUTIC OR PROPHYLACTIC AGENT FOR MULTIPLE SCLEROSIS

A therapeutic or prophylactic agent for multiple sclerosis is disclosed. The therapeutic or prophylactic agent comprises as an effective ingredient a glycine derivative having a specific structure or a pharmaceutically acceptable salt thereof, for example, the below-described compound [(E)-2-(2,6-dichlorobenzamido)-5-[4-(isopropyl-pyrimidin-2-ylamino)phenyl]pent-4-enoic acid]. The therapeutic or prophylactic agent for multiple sclerosis according to the present invention shows the excellent absorbability and in vivo stability when orally administered, and exhibits high therapeutic or prophylactic effects.

GLYCINE DERIVATIVE AND USE THEREOF

A glycine derivative which is, e.g., the following compound (Chemical formula (1)). It is highly effective in the treatment and prevention of inflammatory bowel diseases. Compared to conventional compounds, the compound is excellent in absorbability in oral administration and in vivo stability. The compound can be orally administered and can retain an excellent therapeutic or preventive effect over a longer period.