894401-50-4

Basic information

• Product Name: 2-(2,6-dichlorobenzamido)pent-4-enoic acid methyl ester
• Synonyms: 2-(2,6-dichlorobenzamido)pent-4-enoic acid methyl ester
• CAS NO: 894401-50-4
• Molecular Weight: 302.157
• Mol File: 894401-50-4.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-(2,6-dichlorobenzamido)pent-4-enoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2,6-dichlorobenzamido)pent-4-enoic acid methyl ester(894401-50-4)
• EPA Substance Registry System: 2-(2,6-dichlorobenzamido)pent-4-enoic acid methyl ester(894401-50-4)

Safety Data

• Hazardous Substances Data: 894401-50-4(Hazardous Substances Data)

Upstream product

• 4659-45-4 2,6-Dichlorobenzoyl chloride 
• 1069-48-3 rac-allylglycine 
• 894401-54-8 2-(2,6-dichlorobenzamido)pent-4-enoic acid 
• 67-56-1 methanol 

Downstream Products

• 894402-61-0 (E)-2-(2,6-dichlorobenzamido)-5-[4-(methyl-pyrimidin-2-ylamino)phenyl]pent-4-enoic acid methyl ester 

Relevant articles and documents

THERAPEUTIC OR PROPHYLACTIC AGENT FOR MULTIPLE SCLEROSIS

A therapeutic or prophylactic agent for multiple sclerosis is disclosed. The therapeutic or prophylactic agent comprises as an effective ingredient a glycine derivative having a specific structure or a pharmaceutically acceptable salt thereof, for example, the below-described compound [(E)-2-(2,6-dichlorobenzamido)-5-[4-(isopropyl-pyrimidin-2-ylamino)phenyl]pent-4-enoic acid]. The therapeutic or prophylactic agent for multiple sclerosis according to the present invention shows the excellent absorbability and in vivo stability when orally administered, and exhibits high therapeutic or prophylactic effects.

THERAPEUTIC OR PROPHYLACTIC AGENT FOR ALLERGIC DERMATITIS

A therapeutic or prophylactic agent for allergic dermatitis is disclosed. The therapeutic or prophylactic agent comprises as an effective ingredient a glycine derivative having a specific structure or a pharmaceutically acceptable salt thereof, for example, the below-described compound [(E)-2-(2,6-dichlorobenzamido)-5-[4-(isopropyl-pyrimidin-2-ylamino)phenyl]pent-4-enoic acid]. The therapeutic or prophylactic agent for allergic dermatitis according to the present invention has high therapeutic or prophylactic effect.

GLYCINE DERIVATIVE AND USE THEREOF

A glycine derivative which is, e.g., the following compound (Chemical formula (1)). It is highly effective in the treatment and prevention of inflammatory bowel diseases. Compared to conventional compounds, the compound is excellent in absorbability in oral administration and in vivo stability. The compound can be orally administered and can retain an excellent therapeutic or preventive effect over a longer period.