894790-85-3

Upstream product

• 894790-82-0 (7R,8S)-7-(4-Fluoro-phenyl)-1,4-dioxa-spiro[4.5]decan-8-ol 
• 849674-12-0 (1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl-2,2,2-trichloroethanimidoate 
• 4746-97-8 cyclohexanedione monoethylene ketal 
• 460-00-4 1-Bromo-4-fluorobenzene 
• 225920-05-8 (S)-3,5-bis(trifluoromethyl)-1-phenylethanol 
• 877814-52-3 7-(4-fluorophenyl)-1,4-dioxaspiro[4.5]decan-8-one 
• 912807-27-3 (1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl 2,2,2-trichloroethanimidate 
• 119478-74-9 (S)-4-((tert-butyldimethylsilyl)oxy)cyclohex-2-enone 

Downstream Products

• 894790-89-7 C₂₉H₂₆F₇NO₄S 
• 894790-90-0 C₂₉H₂₆F₇NO₄S 
• 894790-99-9 (5S,6S,7S)-5-[(R)-1-(3,5-Bis-trifluoromethyl-phenyl)-ethoxy]-6-(4-fluoro-phenyl)-7-methyl-azepan-2-one 
• 894790-92-2 (4R,5S)-5-[(R)-1-(3,5-Bis-trifluoromethyl-phenyl)-ethoxy]-4-(4-fluoro-phenyl)-azepan-2-one 
• 894790-91-1 (5S,6S)-5-[(R)-1-(3,5-Bis-trifluoromethyl-phenyl)-ethoxy]-6-(4-fluoro-phenyl)-azepan-2-one 
• 894790-96-6 (2S,3R,4S)-4-[(R)-1-(3,5-Bis-trifluoromethyl-phenyl)-ethoxy]-3-(4-fluoro-phenyl)-2-methyl-cyclohexanone 
• 894790-95-5 (2R,4S,5R)-4-[(R)-1-(3,5-Bis-trifluoromethyl-phenyl)-ethoxy]-5-(4-fluoro-phenyl)-2-methyl-cyclohexanone 
• 894790-87-5 (3R,4S)-4-[(R)-1-(3,5-Bis-trifluoromethyl-phenyl)-ethoxy]-3-(4-fluoro-phenyl)-cyclohexanone 

Relevant academic research and scientific papers

Expeditious synthesis of novel NK1 antagonists based on a 1,2,4-trisubstituted cyclohexane

A stereoselective asymmetric route to novel potent NK1 antagonists based on a 1,2,4-trisubstituted cyclohexane core is discussed.

NK1 antagonists based on seven membered lactam scaffolds

A new class of high affinity hNK1R antagonists based on seven-membered ring cores has been identified. This series, with relatively simple, compact structures, includes compounds with high affinity, good selectivity, and promising in vivo prope