89480-34-2Relevant academic research and scientific papers
Dynamic and Responsive DNA-like Polymers
Mavila, Sudheendran,Worrell, Brady T.,Culver, Heidi R.,Goldman, Trevor M.,Wang, Chen,Lim, Chern-Hooi,Domaille, Dylan W.,Pattanayak, Sankha,McBride, Matthew K.,Musgrave, Charles B.,Bowman, Christopher N.
supporting information, p. 13594 - 13598 (2018/10/24)
The synthesis of thiolactone monomers that mimic natural nucleosides and engage in robust ring opening polymerizations (ROP) is herein described. As each repeat unit contains a thioester functional group, dynamic rearrangement of the polymer is feasible v
Synthesis of 3′- and 5′-nitrooxy pyrimidine nucleoside nitrate esters: "Nitric oxide donor" agents for evaluation as anticancer and antiviral agents
Naimi, Ebrahim,Zhou, Aihua,Khalili, Panteha,Wiebe, Leonard I.,Balzarini, Jan,De Clercq, Erik,Knaus, Edward E.
, p. 995 - 1004 (2007/10/03)
A group of 3′-O-nitro-2′-deoxyuridines, 3′-O -nitro-2′-deoxycytidines and 5′-O-nitro-2′-deoxyuridines possessing a variety of substituents (H, Me, F, I) at the C-5 position were synthesized for evaluation as anticancer/antiviral agents that have the abili
N.M.R. Spectroscopical Investigations on the Conformational Behaviour of Some 2'- and 3'-Halogen-substituted Pyrimidine Nucleosides
Joecks, A.,Koeppel, H.,Schleinitz, K. D.,Cech, D.
, p. 881 - 892 (2007/10/02)
A series of 2'- and 3'-halogenated pyrimidine nucleosides has been synthesized and investigated by 1H, 13C and 19F n.m.r. spectroscopy.The 1H and 13C chemical shifts for the positions 2' and 3' depend linearly but oppositely on the substituent electronegativities XR.The conformational equilibrium N S of the nucleosides in solution is determined.An approximately linear correlation between the prefered gauche-gauche interaction of the exocyclic CH2OH groups and the ribose N conformation has been found.
