895154-77-5

Upstream product

• 91-16-7 1,2-dimethoxybenzene 
• 2859-78-1 4-Bromoveratrole 
• 7787-60-2 bismuth(III) chloride 

Downstream Products

• 78238-97-8 (3,4-dimethoxyphenyl)phenylmethane 
• 79445-44-6 2-(3,4-dimethoxyphenyl)pyridine 
• 79445-45-7 3-(3,4-Dimethoxyphenyl)pyridine 
• 39795-63-6 4-(3,4-dimethoxyphenyl)pyridine 
• 21172-84-9 2,6-bis(3,4-dimethoxyphenyl)pyridine 
• 111770-90-2 5-bromo-2-(3,4-dimethoxyphenyl)pyridine 
• 2026-27-9 3,3',4,4'-tetramethoxylbiphenyl 
• 17190-03-3 4-nitro-3',4'-dimethoxy-2,2'-biphenyl 
• 92552-99-3 2-(3,4-dimethoxyphenyl)-1,3-benzoxazole 

Relevant academic research and scientific papers

Rapid Access to Benzofuran-Based Natural Products through a Concise Synthetic Strategy

A concise strategy is described for the synthesis of ailanthoidol (1), egonol (2), homoegonol (3), demethoxyegonol (4), demethoxyhomoegonol (5), and stemofuran A (6). This approach involves a Pd-catalysed domino cyclization/coupling process using triarylbismuth reagents for the generation of the benzofuran core. Subsequent structural modifications then give the final targets. The high yielding synthesis of the recently isolated natural products egonol-9(Z)-12(Z)-linoleate (2a), 7-demethoxyegonol-9(Z)-12(Z)-linoleate (4a), and 7-demethoxy-egonol-9(Z)-oleate (4b) are also reported.

Tris(polymethoxyphenyl)bismuth derivatives: Synthesis and reactivity

Tris-(polymethoxyphenyl)bismuth diacetate and dichloride derivatives react with C-nucleophiles in basic medium, as well as with N- and O-nucleophiles under copper catalysis to give good to high yields of the corresponding C-, N- and O-arylation products.