92552-99-3

Basic information

• Product Name: 2-(3,4-dimethoxyphenyl)-1,3-benzoxazole
• Synonyms: 2-(3,4-dimethoxyphenyl)-1,3-benzoxazole
• CAS NO: 92552-99-3
• Molecular Weight: 255.273
• Mol File: 92552-99-3.mol
• Article Data: 21

Chemical Properties

• CAS DataBase Reference: 2-(3,4-dimethoxyphenyl)-1,3-benzoxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3,4-dimethoxyphenyl)-1,3-benzoxazole(92552-99-3)
• EPA Substance Registry System: 2-(3,4-dimethoxyphenyl)-1,3-benzoxazole(92552-99-3)

Safety Data

• Hazardous Substances Data: 92552-99-3(Hazardous Substances Data)

Upstream product

• 93-07-2 Veratric acid 
• 95-55-6 2-amino-phenol 
• 1522-76-5 N-(2-chlorophenyl)-3,4-dimethoxybenzamide 
• 75113-82-5 N-(2-bromophenyl)-3,4-dimethoxybenzamide 
• 374695-15-5 2-(3',4'-dihydroxyphenyl)benzothiazole 
• 74-88-4 methyl iodide 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 1522-67-4 N-phenyl-3,4-dimethoxybenzamide 
• 1197285-84-9 C₁₄H₂₀NO₃S⁽¹⁺⁾*I^(1-) 
• 273-53-0 benzoxazole 
• 101959-15-3 3,4-dimethoxyphenyl methanesulfonate 
• 2033-89-8 3,4-dimethoxyphenol 
• 80241-83-4 N**2-(3,4-dimethoxy-benzylidene)aminophenol 
• 93-17-4 3,4-dimethoxyphenylacetonitrile 

Downstream Products

• 1042719-91-4 2-[2-phenyl-4,5-dimethoxyphenyl]-1,3-benzoxazole 
• 1042719-92-5 2-[2-(4-methylphenyl)-4,5-dimethoxyphenyl]-1,3-benzoxazole 
• 1315571-22-2 2-(benzoxazol-2-yl)-4,5-dimethoxyphenyl acetate 

Relevant articles and documents

Environmental benign synthesis of novel double layered nano catalyst and their catalytic activity in synthesis of 2-substituted benzoxazoles

Synthesis of Cu-Al hydrotalcite by co precipitation method is being described. Synthesized nano catalyst has been characterized by powder X-ray diffraction, scanning electron microscopy, FT-IR and thermogravimetric analyses which confirm hydrotalcite-like structure. Effect of molar concentration, catalyst loading, reaction time and catalytic activity have been investigated in the synthesis of benzoxazoles under solvent free conditions using 2-amino phenol and benzoyl chloride. The influence of the hydrotalcite and their different amounts on reactivity was studied. Catalyst can be recycle and used for further reaction without losing its activity.

Development of homogeneous polyamine organocatalyst for the synthesis of 2-aryl-substituted benzimidazole and benzoxazole derivatives

A new polyamine was prepared by the ring opening polymerization of epichlorohydrin and properly characterized. The catalytic property of the prepared polymer was assessed by synthesizing 2-aryl-substituted benzimidazole and benzoxazole derivatives by the conjugation of o-phenylenediamine/o-aminophenol with various aromatic aldehydes in the presence of atmospheric oxygen. Significant attributes of the present synthesis include short reaction time, good to excellent yield, high purity, easy reusability, and room temperature reaction. The reaction was carried out in the absence of any metal catalyst and other cooxidants.

OMS-2/H2O2/Dimethyl Carbonate: An Environmentally-Friendly Heterogeneous Catalytic System for the Oxidative Synthesis of Benzoxazoles at Room Temperature

A manganese octahedral molecular sieve (OMS-2) was found to be an efficient and recyclable heterogeneous catalyst for the oxidative synthesis of benzoxazoles in the gram-scale from phenolic imines at room temperature. H2O2 and biobased reagent dimethyl carbonate (DMC) were successfully employed as the environmentally friendly oxidant and solvent, respectively, in an OMS-2-catalysted redox reaction for the first time. Benzoxazoles could also be obtained from N-substituted 2-aminophenols via Cu(OH)x/OMS-2-catalyzed sequential oxidative transformation at elevated temperatures.