89518-99-0Relevant academic research and scientific papers
NOVEL IMIDAZO-PYRAZINE DERIVATIVES
-
Page/Page column 45; 48-49, (2021/12/31)
The invention provides novel imidazo-pyrazine derivatives having the general formula (I), and pharmaceutically acceptable salts thereof, wherein X, m, n, and R1to R3 are as described herein: formula (I). Further provided are pharmace
Mild, convenient and versatile Cu-mediated synthesis of N-aryl-2-imidazolidinones
Stabile, Paolo,Lamonica, Alessandro,Ribecai, Arianna,Castoldi, Damiano,Guercio, Giuseppe,Curcuruto, Ornella
supporting information; experimental part, p. 3232 - 3235 (2010/08/07)
A mild, general, convenient and practical methodology for the selective copper-mediated mono N-arylation of unprotected 2-imidazolidinone was developed. Strong electron-donating groups and free hydroxy and amino groups on the aryl iodide substrates were well tolerated. The use of n-butanol as the solvent for the copper-catalysed mono-arylation of 2-imidazolidinone is unprecedented.
Heterocyclic compounds
-
Page/Page column 12-13, (2010/11/26)
The present invention relates to the area of blood clotting. The invention relates in particular to certain heterocyclic compounds, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases, and to their use for pro
PYRAZINE DICARBOXAMIDES AND THE USE THEREOF
-
Page/Page column 24, (2010/11/08)
The invention relates to novel pyrazine dicarboxamides, methods for the use thereof, their use for treating and/or preventing diseases as well as to their use for producing medicaments for treating and/or preventing diseases, particularly thromboembolic disorders.
HETEROCYCLIC COMPOUNDS
-
Page/Page column 31, (2010/02/09)
The invention concerns blood clotting. The invention particularly concerns certain heterocyclic compounds, methods for the production thereof, their use for treating and/or preventing diseases, and their use for producing medicaments for treating and/or preventing diseases.
ANTIHYPERTENSIVE 3-(UREIDOCYCLOHEXYLENEAMINO)PROPANE-1,2-DIOL DERIVATIVES
-
, (2008/06/13)
Certain 3-(ureidocyclohexyleneamino)propane-1,2-diol derivatives, such as the compounds of formula III below, represent novel and useful pharmaceutical agents, e.g. potent antihypertensive and cardioactive agents demonstrating both α-and β-adrenergic bloc
