89536-85-6 Usage
Description
BOC-D-MEVAL-OH, also known as tert-butyloxycarbonyl-D-mevalonic acid, is a chemical compound derived from mevalonic acid, a key intermediate in the biosynthesis of isoprenoids and sterols. It is commonly used in organic synthesis and biochemical research, serving as a building block for the creation of complex organic molecules. Notably, BOC-D-MEVAL-OH is used to protect amino groups in peptide synthesis and is a precursor in the production of pharmaceuticals, agrochemicals, and other biologically active compounds. It is also used as a reagent in the preparation of various organic compounds and is available as a white crystalline powder with a molecular weight of 278.32 g/mol.
Uses
Used in Organic Synthesis:
BOC-D-MEVAL-OH is used as a building block for the creation of complex organic molecules, contributing to the development of new compounds with potential applications in various industries.
Used in Biochemical Research:
BOC-D-MEVAL-OH is utilized as a reagent in biochemical research, aiding in the study of isoprenoids and sterols, which are essential components of various biological processes.
Used in Pharmaceutical Production:
BOC-D-MEVAL-OH is used as a precursor in the production of pharmaceuticals, playing a crucial role in the synthesis of biologically active compounds that can be used for the treatment of various diseases and conditions.
Used in Agrochemical Production:
BOC-D-MEVAL-OH is also used as a precursor in the production of agrochemicals, contributing to the development of compounds that can enhance crop yield and protect plants from pests and diseases.
Used in Peptide Synthesis:
BOC-D-MEVAL-OH is used to protect amino groups during peptide synthesis, ensuring the successful formation of desired peptide sequences and facilitating the development of peptide-based drugs and therapeutics.
Check Digit Verification of cas no
The CAS Registry Mumber 89536-85-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,9,5,3 and 6 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 89536-85:
(7*8)+(6*9)+(5*5)+(4*3)+(3*6)+(2*8)+(1*5)=186
186 % 10 = 6
So 89536-85-6 is a valid CAS Registry Number.
89536-85-6Relevant articles and documents
First total synthesis of hoshinoamide A
Liu, Long,Rui, Zihan,Shao, Yutian,Xu, Shengtao,Yang, Yiming,Zhou, Haipin
supporting information, p. 2924 - 2931 (2022/01/12)
Hoshinoamides A, B and C, linear lipopeptides, were isolated from the marine cyanobacterium Caldora penicillata, with potent antiplasmodial activity against chloroquine-sensitive Plasmodium falciparum. Herein, we describe the first total synthesis of hosh
Solution-phase synthesis and biological evaluation of triostin A and its analogues
Hattori, Kozo,Koike, Kota,Okuda, Kensuke,Hirayama, Tasuku,Ebihara, Masahiro,Takenaka, Mei,Nagasawa, Hideko
supporting information, p. 2090 - 2111 (2016/02/18)
Triostin A is a biosynthetic precursor of echinomycin which is one of the most potent hypoxia inducible factor 1 (HIF-1) inhibitors. An improved solution-phase synthesis of triostin A on a preparative scale has been achieved in 17.5% total yield in 13 ste
Total synthesis, absolute configuration, and biological activity of xyloallenoide A
Wang, San-Yong,Xu, Zhong-Liang,Wang, Hui,Li, Chun-Rong,Fu, Li-Wu,Pang, Ji-Yan,Li, Jing,She, Zhi-Gang,Lin, Yong-Cheng
experimental part, p. 973 - 982 (2012/08/08)
The novel natural product xyloallenoide A, isolated from the marine mangrove endophytic fungus from the South China Sea, and its diastereoisomer xyloallenoide A1, which contain N-methyl-substituted amino acids, were synthesized. The absolute configurations of the amino acid units of xyloallenoide A were finally confirmed to be L-Lys, Me-D-Val, and Me-L-Ala. This report represents a practical and attractive alternative for the synthesis of N-methyl-substituted cyclotripeptides. In the preliminary bioassay, synthetic xyloallenoide A showed marginal activities against KB (IC50=9.6 mm) and KBv200 cells (IC50=10.3 μm), and xyloallenoide A1 was inactive against KB and KBv200 cells.
