895525-74-3

Basic information

• Product Name: C₂₂H₁₉ClF₆N₂O₅
• Synonyms: C₂₂H₁₉ClF₆N₂O₅
• CAS NO: 895525-74-3
• Molecular Weight: 540.847
• Mol File: 895525-74-3.mol

Chemical Properties

• CAS DataBase Reference: C₂₂H₁₉ClF₆N₂O₅(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₂H₁₉ClF₆N₂O₅(895525-74-3)
• EPA Substance Registry System: C₂₂H₁₉ClF₆N₂O₅(895525-74-3)

Safety Data

• Hazardous Substances Data: 895525-74-3(Hazardous Substances Data)

Upstream product

• 433-97-6 2-trifluoromethylbenzoic acid 
• 895525-72-1 {[2-(trifluoromethyl)benzoyl]amino}methyl acetate 
• 172527-71-8 diethyl 2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)malonate 

Downstream Products

• 658066-35-4 fluopyram 

Relevant articles and documents

Synthesis method of fluopyram intermediate

The invention discloses a synthesis method of a fluopyram intermediate, and belongs to the field of organic synthesis of pesticides. The process comprises the following steps: by taking methanol amine as a starting raw material, carrying out esterification reaction on methanol amine and acetic anhydride in the presence of acetic acid to obtain methyl aminoacetate, and carrying out amidation reaction on methyl aminoacetate and o-trifluoromethyl benzoyl chloride to obtain N-acetoxymethyl-2-trifluoromethyl benzamide; and finally, carrying out a splicing reaction with diethyl 3-chloro-5-trifluoromethyl-2-pyridylmalonate, so as to obtain the 3-chloro-5-trifluoromethyl-2-pyridylethyl (diethyl ester)-2-trifluoromethyl benzamide. The method adopts a convergent synthesis route, has the characteristics of low raw material cost, high atom economy, high yield, simple process operation and the like, and is suitable for large-scale production.