89604-35-3Relevant academic research and scientific papers
ORTHO METALATION DIRECTED BY α-AMINO ALKOXIDES. AN IMPROVED SYNTHESIS OF ORTHO-SUBSTITUTED ARYL KETONES
Comins, Daniel L.,Brown, Jack D.
, p. 5465 - 5468 (1983)
Ortho-substituted aryl ketones are prepared from N--N-methylbenzamides via ortho lithiation of intermediate α-amino alkoxides, formed in situ by addition of RLi.An ortho lithiation of N--N-methylbenzamide is also described.
