89607-34-1

Basic information

• Product Name: 6-amino-3-methyl-4-(4-nitrophenyl)-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile
• Synonyms: 6-amino-3-methyl-4-(4-nitrophenyl)-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile
• CAS NO: 89607-34-1
• Molecular Formula: C₁₄H₁₁N₅O₃
• Molecular Weight: 297.28
• Mol File: 89607-34-1.mol
• Article Data: 113

Chemical Properties

• Melting Point: 277-280 °C(Solv: ethanol (64-17-5))
• Boiling Point: 620.8±55.0 °C(Predicted)
• Appearance: /
• Density: 1.53±0.1 g/cm3(Predicted)
• PKA: 11.37±0.70(Predicted)
• CAS DataBase Reference: 6-amino-3-methyl-4-(4-nitrophenyl)-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 6-amino-3-methyl-4-(4-nitrophenyl)-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile(89607-34-1)
• EPA Substance Registry System: 6-amino-3-methyl-4-(4-nitrophenyl)-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile(89607-34-1)

Safety Data

• Hazardous Substances Data: 89607-34-1(Hazardous Substances Data)

Upstream product

• 141-97-9 ethyl acetoacetate 
• 555-16-8 4-nitrobenzaldehdye 
• 7803-57-8 hydrazine hydrate 
• 109-77-3 malononitrile 
• 79785-97-0 hydrazine hydrate 
• 4344-87-0 3-hydroxy-5-methyl-1H-pyrazole 
• 2700-23-4 4-Nitrobenzylidenemalononitrile 
• 132712-71-1 5-hydroxy-3-methylpyrazole 
• 623-48-3 ethyl iodoacetae 
• 2033-24-1 cycl-isopropylidene malonate 
• 75-36-5 acetyl chloride 
• 105-45-3 acetoacetic acid methyl ester 
• 108-26-9 3-methyl-2-pyrazoline-5-one 
• 100-63-0 phenylhydrazine 

Downstream Products

• 765312-13-8 1,4-dihydro-(4-nitrophenyl)-5-iminopyrazolo[4',3':5,6]pyrano-[2,3-d]pyrimidin-6-amine 
• 136920-86-0 2-{(E)-2-[6-Amino-5-cyano-4-(4-nitro-phenyl)-1,4-dihydro-pyrano[2,3-c]pyrazol-3-yl]-vinyl}-1-ethyl-quinolinium; iodide 
• 944478-15-3 2-acetyl-3,7-dimethyl-4-(4-nitrophenyl)-2,4-dihydropyrazolo[4',3':5,6]pyrano[2,3-d]pyrimidin-5(6H)-one 
• 950665-88-0 C₁₆H₁₅N₇O₃ 
• 950665-89-1 C₁₈H₁₅N₇O₃ 

Relevant articles and documents

Photophysical study of 6-amino-3-methyl-4-(4-nitrophenyl)-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile and estimation of ground-state and singlet excited-state dipole moments by solvatochromic approaches

An investigation of absorption and fluorescence behaviour of 6-amino-3-methyl-4-(4-nitrophenyl)-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile (NDPPC) at room temperature was carried out using a series of twelve organic solvents with different polarities. Ground and excited state dipole moments were determined experimentally by using Lippert–Mataga polarity function, Bakhshiev solvent polarity parameter, Kawski-Chamma-Viallet solvent polarity parameter, Reichardt's microscopic solvent polarity parameter, Kamlet-Abboud-Taft multiple linear regression and Catalan dipolar polarizibility approach. Due to considerable π- electron density redistribution, the value of excited state dipole moment was found to be greater than that of the ground state. The ground state dipole moment value was determined by quantum chemical method which was used to estimate excited state dipole moment using solvatochromic correlations. Both non-specific solute-solvent interactions and hydrogen bonding interactions were investigated by using Kamlet-Abboud-Taft and Catalan method. TD-DFT (B3LYP/6-311G (d,p)) was used for the determination of HOMO-LUMO energies.

Nano cobalt ferrite encapsulated-silica particles bearing melamine as an easily recyclable catalyst for the synthesis of dihydropyrano[2,3-c]pyrazoles under green conditions

In this research, it was displayed an efficient method for synthesis of 6-amino-2,4-dihydropyrano[2,3-c] pyrazol-5-carbonitrile derivatives by using CoFe2O4 silica supported bearing melamine as a magnetic nanocatalyst. This nanocompo

Concentrated solar radiation-assisted one-pot/multicomponent synthesis of pyranopyrazole derivatives under neat condition

Concentrated solar radiation (CSR)-assisted synthesis of pyranopyrazole derivatives under solvent and catalyst-free condition has been reported in the present protocol. One-pot multicomponent synthesis from aromatic/heteroaldehyde, ethyl acetoacetate, malononitrile, and hydrazine hydrate leads to the final desired compounds in a good yield. This operationally simple methodology has several advantages such as green and clean reaction profile, simple workup and purification procedures, extremely short reaction time, atom efficiency, and being economical. The current energy-efficient method saves almost 98% of energy as compared to the conventional method. Graphical abstract: [Figure not available: see fulltext.]