89622-07-1Relevant academic research and scientific papers
PYRIMIDINE AND PYRIDINE DERIVATIVES AND USE IN TREATMENT, AMELIORATION OR PREVENTION OF INFLUENZA THEREOF
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Page/Page column 149, (2017/12/28)
Provided herein is a compound of formula (I), optionally in the form of a pharmaceutically acceptable salt, solvate, polymorph, prodrug, codrug, cocrystal, tautomer, racemate, enantiomer, or diastereomer or mixture thereof, which is useful in treating, ameliorating or preventing influenza.
REGIOSELECTIVE SYNTHESIS OF (+/-)-GABACULINE HYDROCHLORIDE
Frater, G.,Mueller, U.,Schoepfer, U.
, p. 281 - 284 (2007/10/02)
3-Cyclohexenecarboxylic acid (2) has been functionalized to the protected amino acid 5 in a novel reaction sequence, the crucial step being the acid catalysed cyclization of the γ,δ-unsaturated isocyanate 3 to the bicyclic lactam 4. 5 was converted into gabaculine hydrochloride (l HCl).
