89656-44-0

Basic information

• Product Name: Piperidine, 2-(2-propenyl)-
• CAS NO: 89656-44-0
• Molecular Formula: C8H15N
• Molecular Weight: 125.214
• Mol File: 89656-44-0.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: Piperidine, 2-(2-propenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Piperidine, 2-(2-propenyl)-(89656-44-0)
• EPA Substance Registry System: Piperidine, 2-(2-propenyl)-(89656-44-0)

Safety Data

• Hazardous Substances Data: 89656-44-0(Hazardous Substances Data)

Upstream product

• 131248-69-6 1-[(E)-tert-Butylimino-methyl]-piperidin-2-one 
• 131248-73-2 2-methoxy piperidine N-t-butyl formamidine 
• 131248-72-1 1-[(E)-tert-Butylimino-methyl]-piperidin-2-ol 
• 675-20-7 piperidin-2-one 
• 85152-52-9 N-(N'-tert-butylformimidoyl)piperidine 
• 34418-91-2 2,3,4,5-tetrahydropyridine N-oxide 
• 110-89-4 piperidine 
• 705282-32-2 2-(3,3-diiodo-2-propenyl)-1-piperidinecarboxylic acid tert-butyl ester 
• 170491-61-9 2-(2-oxoethyl)-1-piperidinecarboxylic acid tert-butyl ester 
• 118811-03-3 tert-butyl 2-(2-hydroxyethyl)piperidine-1-carboxylate 
• 1484-84-0 2(RS)-(2-hydroxyethyl)piperidine 
• 182343-60-8 2-(2-propenyl)-1-piperidinecarboxylic acid tert-butyl ester 
• 89656-41-7 [1-(2-Allyl-piperidin-1-yl)-meth-(E)-ylidene]-tert-butyl-amine 
• 95683-74-2 3-allyl-2-piperidinone 

Downstream Products

• 1613330-97-4 (±)-2-allyl-N-(4-methoxyphenyl)piperidine-1-sulfonamide 
• 634878-89-0 2-allyl-1-benzylpiperidine 
• 955404-30-5 O-benzoyl-2-allylpiperidin-1-ol 
• 182343-62-0 1-Benzoyl-2-(prop-2-enyl)piperidine 
• 705282-43-5 1-chloroformyl-2-(2-propenyl)piperidine 
• 3238-60-6 rac-coniine 
• 491-40-7 quinolizidin-4-one 

Relevant articles and documents

Electrophilic formamidines. Organometallic addition to 2-methoxy pyrrolidine or piperidine N-t-butyl formamidines. Formation of 2-substituted pyrrolidines and piperidines

The title compounds were prepared by addition of Grignard reagents to methoxyformamidines 6 and 8 in ether at room temperature. Hydrolysis gives the free secondary amines, or in cases of volatile products, their thiourea derivatives.

Regioselective synthesis of azetidines or pyrrolidines by selenium-induced cyclization of secondary homoallylic amines

Azetidines or pyrrolidines can be regioselectively obtained by selenocyclization of homoallylic amines, according to the double bond substitution.

Studies toward labeling cytisine with [11C]phosgene: Rapid synthesis of a δ-lactam involving a new chemoselective lithiation-annulation method

With the aim of the radiolabeling of cytisine, a potent agonist of nicotinic receptors, with [11C]-phosgene, the rapid synthesis of a lactam model of our target has been studied. The key step of the δ-lactam formation is a new chemoselective lithiation-annulation method, under high dilution, of a suitable piperidinylcarbamoyl chloride. This precursor was obtained from (2-hydroxyethyl)-piperidine in a linear synthetic sequence involving a Corey-Fuchs olefination of the corresponding aldehyde, followed by a selective reduction, using a diimide equivalent, of an iodoalkyne into a (Z)-iodopropene piperidine. This alkene served as main precursor to study the cyclization according to several procedures using phosgene as the required carbonylating reagent.