896722-53-5 Usage
Description
1H-Pyrrolo[2,3-b]pyridine, 6-methoxyis a heterocyclic chemical compound with the molecular formula C10H9NO. It features a pyrrolopyridine ring system with a methoxy group at the 6-position. 1H-Pyrrolo[2,3-b]pyridine, 6-methoxyis known for its potential biological activities and is widely used in organic synthesis and pharmaceutical research. Its unique structure and properties make it a valuable building block for developing new drugs and agrochemicals. Furthermore, 1H-Pyrrolo[2,3-b]pyridine, 6-methoxyhas been studied for its potential antitumor and antiviral properties, highlighting its importance in research and exploration.
Uses
Used in Pharmaceutical Research and Development:
1H-Pyrrolo[2,3-b]pyridine, 6-methoxyis used as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structure and properties make it a valuable building block for the development of new drugs with potential therapeutic applications.
Used in Organic Synthesis:
1H-Pyrrolo[2,3-b]pyridine, 6-methoxyserves as a versatile starting material in organic synthesis, allowing for the preparation of a wide range of chemical compounds with diverse applications.
Used in Agrochemical Development:
1H-Pyrrolo[2,3-b]pyridine, 6-methoxyis utilized in the development of new agrochemicals, such as pesticides and herbicides, due to its potential biological activities and ability to be modified for specific applications.
Used in Antitumor Research:
1H-Pyrrolo[2,3-b]pyridine, 6-methoxyis studied for its potential antitumor properties, making it an important target for research in the development of novel cancer therapies.
Used in Antiviral Research:
1H-Pyrrolo[2,3-b]pyridine, 6-methoxyis also investigated for its potential antiviral properties, contributing to the search for new antiviral agents to combat viral infections.
Check Digit Verification of cas no
The CAS Registry Mumber 896722-53-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,9,6,7,2 and 2 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 896722-53:
(8*8)+(7*9)+(6*6)+(5*7)+(4*2)+(3*2)+(2*5)+(1*3)=225
225 % 10 = 5
So 896722-53-5 is a valid CAS Registry Number.
InChI:InChI=1/C8H8N2O/c1-11-7-3-2-6-4-5-9-8(6)10-7/h2-5H,1H3,(H,9,10)
896722-53-5Relevant articles and documents
Cu(II)-catalyzed sulfonylation of 7-azaindoles using DABSO as SO2-Source and its mechanistic study
Urvashi,Dar, Mohammad Ovais,Bharatam, Prasad V.,Das, Parthasarathi,Kukreti, Shrikant,Tandon, Vibha
, (2020/06/23)
DABSO mediated sulfonylation of iodinated 7-azaindoles was achieved for the first time through sulfonylative Suzuki-Miyaura cross coupling (SMC) reaction under mild conditions giving good yields of sulfonylated 7-azaindole derivatives. Interestingly, control experiments suggest that present method involves in-situ generation of ArSO2 free radical followed by the key steps of SMC reaction. Scope of the reaction was explored with both electronically different and bulky group carrying boronic acids as coupling partner. The sulfonylation is scalable and occurred selectively at iodo group, irrespective of its position on azaindole. Moreover, the proposed mechanism has been supported by electron paramagnetic resonance (EPR) and density functional theory (DFT) calculations.
Scaffold-hopping strategy: Synthesis and biological evaluation of 5,6-fused bicyclic heteroaromatics to identify orally bioavailable anticancer agents
Tung, Yen-Shih,Coumar, Mohane Selvaraj,Wu, Yu-Shan,Shiao, Hui-Yi,Chang, Jang-Yang,Liou, Jing-Ping,Shukla, Paritosh,Chang, Chun-Wei,Chang, Chi-Yen,Kuo, Ching-Chuan,Yeh, Teng-Kuang,Lin, Chin-Yu,Wu, Jian-Sung,Wu, Su-Ying,Liao, Chun-Chen,Hsieh, Hsing-Pang
, p. 3076 - 3080 (2011/06/25)
Utilizing scaffold-hopping drug-design strategy, we sought to identify a backup drug candidate for BPR0L075 (1), an indole-based anticancer agent. For this purpose, 5,6-fused bicyclic heteroaromatic scaffolds were designed and synthesized through shufflin
The first practical and efficient one-pot synthesis of 6-substituted 7-azaindoles via a Reissert-Henze reaction
Storz, Thomas,Bartberger, Michael D.,Sukits, Steven,Wilde, Chris,Soukup, Troy
, p. 201 - 214 (2008/12/21)
A variety of 6-substituted 7-azaindoles (30 examples) were obtained via selective O-methylation of 7-azaindole-N-oxide m-chlorobenzoic acid salt and subsequent, base-catalyzed one-pot reaction with a range of N-, O-, S-nucleophiles or cyanide. Georg Thieme Verlag Stuttgart.