89692-65-9Relevant academic research and scientific papers
1,1-Dioxo-5,6-dihydro-[4,1,2]oxathiazines, a novel class of 11?-HSD1 inhibitors for the treatment of diabetes
B?hme, Thomas,Engel, Christian K.,Farjot, Géraldine,Güssregen, Stefan,Haack, Torsten,Tschank, Georg,Ritter, Kurt
, p. 4685 - 4691 (2013/08/15)
Racemic cis-1,1-dioxo-5,6-dihydro-[4,1,2]oxathiazine derivative 4a was isolated as an impurity in a sample of a hit from a HTS campaign on 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1). After separation by chiral chromatography the 4a-S, 8a-R enantio
Acyl and Sulfonyl Isocyanates ib β-Lactam Synthesis
Barrett, Anthony G. M.,Betts, Michael J.,Fenwick, Ashley
, p. 169 - 175 (2007/10/02)
The preparation of β-lactams from the reactions of several acyl and sulfonyl activated isocyanates with alkenes was studied.Three compounds, (2,2,2-trichloroethoxy)sulfonyl, 2,2,2-trichloroethane sulfonyl, and trifluoroacetyl isocyanates, were shown to be
