897030-44-3

Upstream product

• 104-88-1 4-chlorobenzaldehyde 
• 89-25-8 edaravone 
• 184534-55-2 1-(5-hydroxy-3-methyl-1-phenyl-4-pyrazyl)-1-(3'-indolyl)-1-(4''-chlorophenyl)methane 

Downstream Products

• 184534-55-2 1-(5-hydroxy-3-methyl-1-phenyl-4-pyrazyl)-1-(3'-indolyl)-1-(4''-chlorophenyl)methane 
• 125732-45-8 4-[(4-Chloro-phenyl)-(2-piperidin-1-yl-cyclohex-1-enyl)-methyl]-5-methyl-2-phenyl-2,4-dihydro-pyrazol-3-one 
• 135763-59-6 C₃₃H₃₀ClN₇O₂ 
• 6265-91-4 2-(4-chlorophenyl)benzothiazole 
• 89-25-8 edaravone 
• 135763-51-8 4-(4-Chloro-phenyl)-3-methyl-8a-morpholin-4-yl-1-phenyl-1,4,4a,5,6,7,8,8a-octahydro-chromeno[2,3-c]pyrazole 

Relevant academic research and scientific papers

Synthesis, characterization and biological applications of substituted pyrazolone core based platinum(II) organometallic compounds

New series of organometallic platinum(II) compounds (I-VI) containing the 2-phenyl-5-methyl pyrazole-3-one derivatives ligands (L1-L6) were synthesized and characterized by spectroscopic and physicochemical techniques. The synthesize

Detection and Treatment of Schizophrenia

The present invention provides a method for diagnosing schizophrenia, and a schizophrenia diagnostic reagent or device for use in the method. The present invention further provides a therapeutic or ameliorating agent for schizophrenia, which is effective for the treatment or amelioration of schizophrenia. The therapeutic or ameliorating agent for schizophrenia contains a carbonyl scavenger or a carbonyl-modified protein formation inhibitor as an active ingredient. The method for diagnosing schizophrenia according to the present invention includes measuring at least one parameter in a subject, the parameter being selected from the group consisting of: (1) a genetic abnormality of glyoxalase I gene; (2) the expression level or activity of glyoxalase I in a biological sample; (3) the amount of a carbonyl compound or a carbonyl-modified protein that is a protein modified with the carbonyl compound; and (4) the amount of pyridoxal in a biological sample.

Microwave assisted one pot synthesis of 8-methyl-3,6,9-triphenyl-5,6- dihydro-9H-pyrazolo[3,4-e][1,2,4]triazolo[3,4-b][1,3,4]thiadiazepine

A facile one step synthesis of novel 8-methyl-3,6,9-triphenyl-5,6-dihydro- 9H-pyrazolo[3,4-e][1,2,4]triazolo[3,4-b][1,3,4]thiadiazepines 3a-1 by the reaction of (4E)-4-benzylidene-5-methyl-2-phenyl-3,4-dihydropyrazol-3,2H-ones 1a-f and 4-amino-5-phenyl-4H

The solid-state Michael addition of indole to 4-arylidene-3-methyl-5- pyrazolone

The Michael addition reactions of indole to 4-arylidene-3-methyl-1- phenyl-5-pyrazolone 1 were investigated in the solid state, by which a series of new compounds, 1-aryl-1-(3-indolyl)-1-(3'-methyl-1'-phenyl-5'-pyrazolon- 4'-yl)methanes 2, were easily obtained. This provides a feasible method of preparing novel compounds containing two heterocyclic groups at the same carbon.