89723-51-3Relevant articles and documents
Total synthesis of the callipeltoside Aglycon
Paterson, Ian,Davies, Robert D. M.,Marquez, Rodolfo
, p. 603 - 607 (2007/10/03)
Following macrolactonization, a Sonogashira coupling leads efficiently from 1 and 2 to the aglycon of the structurally unique cytotoxic macrolide callipeltoside A, isolated in tiny quantities from the lithistid sponge Callipelta sp. Key steps in the prepa
FORMATION OF 1-SUBSTITUTED PYRROLES IN REACTION OF 2-CHLOROCYCLOPROPANECARBOXALDEHYDES WITH PRIMARY AMINES
Nadim, Al' Mokhana,Romashin, Yu. N.,Kulinkovich, O. G.
, p. 1419 - 1422 (2007/10/02)
Reactions of 2-chlorocyclopropanecarboxaldehydes with primary amines in boiling DMF lead in good yield to 1-substituted pyrroles. 2-Chlorocyclopropanecarboxaldehydes were synthesized by the stereoselective reduction of the corresponding 2,2-dichlorocyclopropanemethanols with lithium tetrahydroaluminate with the subsequent oxidation of the mixture of stereoisomeric 2-chlorocyclopropanemethanols with pyridinium chlorochromate.