89736-81-2Relevant academic research and scientific papers
Synthesis of heterocycles with MF/Al2O3 base-systems: 2-arylbenzofuranes and 2,3-diarylisoquinolin-1(2H)-ones
Hellwinkel,Goke
, p. 1135 - 1141 (2007/10/02)
2-Benzyloxybenzaldehydes, -acetophenones and -benzophenones substituted in the benzyl part with electron-withdrawing groups, cyclize easily to 2-arylbenzofuranes by using a standardized KF- or CsF-Al2O3 base system. An efficient one-pot synthesis for 2,3-diarylisoquinolin-1(2H)-ones is possible by reacting a variety of arene carbaldehyde anils with phthalides under the same reaction conditions.
Reactions of Glutaconic and Homophthalic Anhydrides with Imidates, Imidoyl Chlorides, and 1-Chloroisoquinoline
Stanoeva, Elena,Haimova, Marietta,Ognyanov, Vassil
, p. 389 - 394 (2007/10/02)
Glutaconic anhydride (9) reacts with N-substituted benzimidoyl chlorides 3 to give the corresponding (Z)-3-pyrandiones 12, whereas with 1-chloroisoquinoline (4) the benzoquinolizinone 13 is obtained.The reactions of α-methylhomophthalic anhydride (10) with 3 and the imidate 7 lead to the 1(2H)-isoquinolinones 14 and 19, respectively, and with 4 to the 13-methyldibenzoquinolizinone 15.The interaction of homophthalic anhydrides 1a, b with 3 aiming at the preparation of α-condensation products is investigated.
