897771-13-0Relevant articles and documents
Evaluation of NTF1836 as an inhibitor of the mycothiol biosynthetic enzyme MshC in growing and non-replicating Mycobacterium tuberculosis
Newton, Gerald L.,Buchmeier, Nancy,La Clair, James J.,Fahey, Robert C.
, p. 3956 - 3964 (2011)
The mycothiol biosynthesis enzyme MshC catalyzes the ligation of cysteine with the pseudodisaccharide GlcN-Ins and has been identified as an essential enzyme in Mycobacterium tuberculosis. We now report on the development of NTF1836 as a micromolar inhibi