89816-77-3Relevant academic research and scientific papers
Synthesis of 4,6-dimethyldibenzothiophene and 1,2,3,4-tetrahydro-4,6- dimethyldibenzothiophene via Tilak annulation
Xu, Xiaoying,Li, Xiang,Wang, Anjie,Sun, Yinyong,Schweizer, W. Bernd,Prins, Roel
, p. 1754 - 1763 (2011)
1,2,3,4-Tetrahydro-4,6-dimethyldibenzothiophene was prepared by coupling 2-bromo-3-methylcyclohexanone with 2-methylbenzenethiol and annulating the product with the aid of polyphosphoric acid. A mixture of 1,2,3,4-tetrahydro-4, 6-dimethyldibenzothiophene and 4,6-dimethyldibenzothiophene was prepared by coupling 2-bromo-3-methylcyclohex-2-en-1-one with 2-methylbenzenethiol and annulating the product with the aid of polyphosphoric acid. 2-Bromo-3- methylcyclohexanone was synthesized by conjugate addition of Me3Al to 2-bromocyclohex-2-en-1-one with CuBr as catalyst and 2-bromo-3-methylcyclohex- 2-en-1-one by bromination-elimination of 3-methylcyclohex-2-en-1-one. 1,2,3,4,4a,9b-Hexahydro-4,6-dimethyldibenzothiophene was prepared by reduction of 1,2,3,4-tetrahydro-4,6-dimethyldibenzothiophene with Zn and CF 3COOH. Copyright
