898520-97-3

Upstream product

• 18978-78-4 2-methyl-8-aminoquinoline 
• 122-01-0 4-chloro-benzoyl chloride 
• 74-11-3 para-chlorobenzoic acid 

Downstream Products

• 1169391-72-3 N-(2-(1H-benzo[d]imidazol-2-yl)quinolin-8-yl)-4-chlorobenzamide 
• 1346643-60-4 dimethylaluminum 4-chloro-N-(2-methylquinolin-8-yl)benzamidate 
• 1227096-17-4 η5-cyclopentadienyl[N-(2-methylquinolin-8-yl)-p-chlorobenzamide]titanium dichloride 

Relevant academic research and scientific papers

QUINOLINES THAT MODULATE SERCA AND THEIR USE FOR TREATING DISEASE

Provided herein are quinolines, e.g., a compound of Formula I, pharmaceutical compositions thereof, and methods of their use for treating, preventing, or ameliorating one or more symptoms of a neurological disease, neurodegenerative disorder, or diabetes. Also provided herein are methods of their use for modulating the activity of a sarcoplasmic/endoplasmic reticulum C2+ ATPase.

QUINOLINES AND THEIR USE FOR TREATING ENDOPLASMIC RETICULUM STRESS-CAUSED DISEASES

Provided herein are quinolines, e.g., a compound of Formula (I) or (IB), pharmaceutical compositions thereof, and methods of their use for treating, preventing, or ameliorating one or more symptoms of an endoplasmic reticulum stress-caused disease. Also provided herein are methods of their use for reducing endoplasmic reticulum stress and modulating the activity of a sarcoplasmic/endoplasmic reticulum Ca2+ ATPase.

Synthesis, characterization and ethylene oligomerization of nickel complexes bearing N-(2-(1H-benzo[d]imidazol-2-yl)quinolin-8-yl)benzamide derivatives

A series of N-(2-(1-R-1H-benzo[d]imidazol-2-yl)quinolin-8-yl)-2-R 1-4-R2-benzamide derivatives (5-12) was synthesized and characterized. These compounds 5-11 (5: R = H, R1 = H, R2 = H; 6: R = H, R1 =