898909-73-4Relevant academic research and scientific papers
Chemically induced dimerization of human nonpancreatic secretory phospholipase A2 by bis-indole derivatives
Zhou, Lu,Fang, Chao,Wei, Ping,Liu, Shiyong,Liu, Ying,Lai, Luhua
experimental part, p. 3360 - 3366 (2009/04/06)
A series of novel bis-indole compounds, 1,ω-bis(((3-acetamino-5- methoxy-2-methylindole)-2-methylene)phenoxy)alkane, have been designed and synthesized on the basis of the enzyme structure of human nonpancreatic secretory phospholipase A2 (hnps PLA2). The
Synthesis of aromatic analogs of 8(S)-HETE and their biological evaluation as activators of the PPAR nuclear receptors
Caijo, Frederic,Mosset, Paul,Gree, Rene,Audinot-Bouchez, Valerie,Boutin, Jean,Renard, Pierre,Caignard, Daniel-Henri,Dacquet, Catherine
, p. 2181 - 2196 (2007/10/03)
A new family of 8-HETE analogs has been synthesized as dual PPAR α and γ agonists. A versatile strategy has been developed to allow modulations not only around the aromatic core but also on the side chains of these analogs. The affinity of these compounds
