898909-89-2Relevant academic research and scientific papers
Synthesis of aromatic analogs of 8(S)-HETE and their biological evaluation as activators of the PPAR nuclear receptors
Caijo, Frederic,Mosset, Paul,Gree, Rene,Audinot-Bouchez, Valerie,Boutin, Jean,Renard, Pierre,Caignard, Daniel-Henri,Dacquet, Catherine
, p. 2181 - 2196 (2007/10/03)
A new family of 8-HETE analogs has been synthesized as dual PPAR α and γ agonists. A versatile strategy has been developed to allow modulations not only around the aromatic core but also on the side chains of these analogs. The affinity of these compounds
