89891-69-0

Basic information

• Product Name: 2-Bromo-4-cyanobenzaldehyde
• Synonyms: 2-Bromo-4-cyanobenzaldehyde;3-BroMo-4-forMylbenzonitrile;2-bromo-4-cyanobenzladehyde
• CAS NO: 89891-69-0
• Molecular Formula: C₈H₄BrNO
• Molecular Weight: 210.04
• Mol File: 89891-69-0.mol

Chemical Properties

• Melting Point: 118-120℃
• Boiling Point: 308℃
• Flash Point: 140℃
• Appearance: /
• Density: 1.65
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 2-Bromo-4-cyanobenzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Bromo-4-cyanobenzaldehyde(89891-69-0)
• EPA Substance Registry System: 2-Bromo-4-cyanobenzaldehyde(89891-69-0)

Safety Data

• Hazardous Substances Data: 89891-69-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-Bromo-4-cyanobenzaldehyde is used as a reactant for the synthesis of various pharmaceuticals, contributing to the development of new drugs and therapeutic agents. Its unique structure with bromine and cyano groups enables the creation of complex molecules with potential medicinal properties.
Used in Agrochemical Industry:
In the agrochemical sector, 2-Bromo-4-cyanobenzaldehyde serves as a reactant for the production of agrochemicals, such as pesticides and herbicides. Its versatility in organic synthesis allows for the development of effective compounds to protect crops and enhance agricultural productivity.
Used in Dye Industry:
2-Bromo-4-cyanobenzaldehyde is utilized as a reactant in the synthesis of dyes, providing a wide range of color options for various applications, including textiles, plastics, and printing inks. Its chemical properties facilitate the creation of stable and vibrant dyes with diverse color characteristics.
Used as an Intermediate in Organic Synthesis:
Beyond its direct applications, 2-Bromo-4-cyanobenzaldehyde is also used as an intermediate in the synthesis of other organic compounds. Its presence in the molecular structure of various complex molecules makes it an essential component in the development of advanced materials and chemical products.

Upstream product

• 89892-39-7 3-bromo-4-(bromomethyl)benzonitrile 
• 42872-74-2 3-bromo-4-methyl-benzonitrile 
• 33499-34-2 4-cyanobenzaldehyde O-methyloxime 
• 105-07-7 4-cyanobenzaldehyde 
• 1381846-22-5 3-bromo-4-(dibromomethyl)benzonitrile 
• 104-85-8 para-methylbenzonitrile 

Downstream Products

• 90110-98-8 3-bromo-4-(hydroxymethyl)benzonitrile 
• 1427086-31-4 [4-(aminomethyl)-2-bromophenyl]methanol 
• 1427086-98-3 tert-butyl [(Z)-{[3-bromo-4-(hydroxymethyl)benzyl]amino} {[( tert-butyloxy)carbonyl]amino}methylidene]carbamate 
• 1427085-35-5 1-[3-bromo-4-(fluoromethyl)benzyl]guanidine trfluoroacetic acid salt 
• 1427087-11-3 tert-butyl [(Z)-{[3-bromo-4-(bromomethyl)benzyl]amino} {[( tert-butyloxy)carbonyl]amino}methylidene]carbamate 
• 1427085-39-9 1-{3-bromo-4-[(2-fluoroethoxy)methyl]benzyl}guanidine trfluoroacetic acid salt 
• 1427085-41-3 1-{3-bromo-4-[(2-[¹⁸F]fluoroethoxy)methyl]benzyl}guanidine trifluoroacetic acid salt 

Relevant articles and documents

Preparation method of 2 -bromine -4-nitrile benzaldehyde

The invention relates to a preparation method of 2 - bromo -4 nitrile benzaldehyde, and belongs to the field of pharmaceutical chemistry. The preparation method can be used for preparing 2 - bromo -4 nitrile benzaldehyde by taking methylbenzonitrile as a

PYRIMIDINYL GROUP-CONTAINING TRICYCLIC COMPOUND SERVING AS C-MET INHIBITOR

Disclosed are a pyrimidinyl group-containing tricyclic compound and applications thereof in preparing a cancer-treating medicament. Specifically disclosed are a compound as represented by formula (I), a pharmaceutically acceptable salt of same, or an isomer thereof.

Indole compound as well as preparation method, pharmaceutical composition and application thereof

The invention discloses an indole compound as well as a preparation method, a pharmaceutical composition and an application thereof. Specifically, the invention relates to an indole derivative as shown in a general formula I and a medicinal salt thereof, a preparation method of the indole derivative, a composition containing one or more compounds, and applications of the compounds in preparation of medicines for preventing and/or treating diseases related to IDO1 and/or TDO.

Diverse ortho-C(sp2)-H functionalization of benzaldehydes using transient directing groups

Pd-catalyzed C-H functionalizations promoted by transient directing groups remain largely limited to C-H arylation only. Herein, we report a diverse set of ortho-C(sp2)-H functionalizations of benzaldehyde substrates using the transient directing group strategy. Without installing any auxiliary directing group, Pd(II)-catalyzed C-H arylation, chlorination, bromination, and Ir(III)-catalyzed amidation, could be achieved on benzaldehyde substrates. The transient directing groups formed in situ via imine linkage can override other coordinating functional groups capable of directing C-H activation or catalyst poisoning, significantly expanding the scope for metal-catalyzed C-H functionalization of benzaldehydes. The utility of this approach is demonstrated through multiple applications, including late-stage diversification of a drug analogue.

COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS

The present invention relates to systems, compositions, and methods for the synthesis and use of imaging agents, or precursors thereof. An imaging agent precursor may be converted to an imaging agent using the methods described herein. In some cases, the

Selective ortho -bromination of substituted benzaldoximes using Pd-catalyzed C-H activation: Application to the synthesis of substituted 2-bromobenzaldehydes

Substituted 2-bromobenzaldehydes were synthesized from benzaldehydes using a three-step sequence involving a selective palladium-catalyzed ortho-bromination as the key step. O-Methyloxime serves as a directing group in this reaction. A rapid deprotection of substituted 2-bromobenzaldoximes afforded substituted 2-bromobenzaldehydes with good overall yields.