89900-91-4

Usage

Uses

Used in Industrial Processes:
Methyl 3-bromo[1,1'-biphenyl]-4-carboxylate is used as an intermediate in saponification processes, which are essential for the production of various industrial chemicals and materials.
Used in Pharmaceutical and Organic Synthesis:
Methyl 3-bromo[1,1'-biphenyl]-4-carboxylate is used as a reagent in pharmaceutical and organic synthesis, contributing to the development of new drugs and organic compounds with potential applications in various fields.

Upstream product

• 591-18-4 1-Bromo-3-iodobenzene 
• 99768-12-4 4-methoxycarbonylphenylboronic acid 
• 67-56-1 methanol 
• 5737-83-7 3'-bromobiphenyl-4-carboxylic acid 

Downstream Products

• 5737-83-7 3'-bromobiphenyl-4-carboxylic acid 

Relevant academic research and scientific papers

NOVEL LXR MODULATORS WITH BICYCLIC CORE MOIETY

The present invention relates to bicyclic compounds (e.g. indoles) containing a sulfonyl moiety, which bind to the liver X receptor (LXRα and/or LΧΚβ) and act preferably as inverse agonists of LXR.

APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES

Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein.

The Effects of Substituents on the Rate of Saponification of Biphenyl-4-carboxylates

Second-order rate constants have been measured for the saponification of methyl 2'-, 3'-, and 4'-substituted biphenyl-4-carboxylates at several temperatures in 85percent (w/w) methanol-water and activation parameters have been calculated.The Hammett equation applies very well to the saponification of 3'- and 4'-substituted biphenyl-4-carboxylates with ?-constants evaluated by the FMMF method.The effect of 2'-substituents is understandable in terms of ?-electron steric effects.